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Gene

MAP4K5

mitogen-activated protein kinase kinase kinase kinase 5

Summary

Cytogenetic location
14q22.1
Coordinates
Chromosome 14: 50,418,521–50,532,569 (GRCh38)
Exons
33 exons across 114 kb
Protein
846 amino acids
Also known as
KHS1, GCKR, KHS
MANE Select transcript
ENST00000682126.1NM_006575.6
Locus type
gene with protein product

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads MAP4K5 yet. The test sequences your whole genome, so your data includes it all the same.

How MAP4K5 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 14, with a bracket where MAP4K5 sits. MAP4K5 and 11 genes near it on chromosome 14, from 49,975,545 to 50,975,544.Chromosome 1414q22.1p13p12p11.2p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.11q32.12q32.13q32.2q32.31q32.32q32.3350 Mb50.2 Mb50.4 Mb50.6 Mb50.8 MbVCPKMT: 50,108,631–50,116,600, reverse strandVCPKMTSOS2: 50,116,801–50,231,930, reverse strandSOS2L2HGDH: 50,237,563–50,312,243, reverse strandL2HGDHDMAC2L: 50,311,516–50,356,756, forward strandDMAC2LCDKL1: 50,326,265–50,416,461, reverse strandCDKL1MAP4K5: 50,418,521–50,532,569, reverse strandMAP4K5ATL1: 50,532,509–50,634,017, forward strandATL1SAV1: 50,626,616–50,668,600, reverse strandSAV1NIN: 50,719,763–50,832,038, reverse strandNINPYGL: 50,857,891–50,944,734, reverse strandPYGLABHD12B: 50,872,046–50,904,970, forward strandABHD12BTRIM9: 50,975,254–51,096,084, reverse strandTRIM9Diagram of MAP4K5: 33 exons on the reverse strand of chromosome 14Exon 33: 50,418,521–50,420,106, 1,586 basesExon 32: 50,423,121–50,423,176, 56 basesExon 31: 50,425,907–50,425,977, 71 basesExon 30: 50,428,662–50,428,754, 93 basesExon 29: 50,429,192–50,429,260, 69 basesExon 28: 50,434,394–50,434,571, 178 basesExon 27: 50,434,962–50,435,065, 104 basesExon 26: 50,437,476–50,437,534, 59 basesExon 25: 50,437,894–50,438,008, 115 basesExon 24: 50,438,092–50,438,094, 3 basesExon 23: 50,440,013–50,440,073, 61 basesExon 22: 50,440,362–50,440,441, 80 basesExon 21: 50,442,732–50,442,816, 85 basesExon 20: 50,443,729–50,443,770, 42 basesExon 19: 50,443,939–50,444,036, 98 basesExon 18: 50,445,041–50,445,194, 154 basesExon 17: 50,446,079–50,446,121, 43 basesExon 16: 50,447,414–50,447,481, 68 basesExon 15: 50,448,774–50,448,832, 59 basesExon 14: 50,456,516–50,456,594, 79 basesExon 13: 50,462,665–50,462,781, 117 basesExon 12: 50,464,052–50,464,133, 82 basesExon 11: 50,466,583–50,466,645, 63 basesExon 10: 50,468,651–50,468,782, 132 basesExon 9: 50,475,077–50,475,149, 73 basesExon 8: 50,476,128–50,476,170, 43 basesExon 7: 50,476,259–50,476,306, 48 basesExon 6: 50,482,361–50,482,416, 56 basesExon 5: 50,485,578–50,485,642, 65 basesExon 4: 50,486,104–50,486,194, 91 basesExon 3: 50,504,800–50,504,857, 58 basesExon 2: 50,531,942–50,532,158, 217 basesExon 1: 50,532,448–50,532,569, 122 bases333025201510515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.3 kb of the gene's 114 kb; 2,541 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). MAP4K5 gene: mitogen-activated protein kinase kinase kinase kinase 5. Retrieved 16 October 2026, from https://dantelabs.com/genes/map4k5

Vancouver

Dante Labs. MAP4K5 gene: mitogen-activated protein kinase kinase kinase kinase 5 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/map4k5

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