Skip to content
Use your HSA or FSA funds

Gene

LGR5

leucine rich repeat containing G protein-coupled receptor 5

Summary

Cytogenetic location
12q21.1
Coordinates
Chromosome 12: 71,439,798–71,586,310 (GRCh38)
Exons
18 exons across 146.5 kb
Protein
907 amino acids
Also known as
HG38, FEX
Previous symbols
GPR67, GPR49
MANE Select transcript
ENST00000266674.10NM_003667.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads LGR5 yet. The test sequences your whole genome, so your data includes it all the same.

How LGR5 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 12, with a bracket where LGR5 sits. LGR5 and 8 genes near it on chromosome 12, from 71,013,054 to 72,013,053.Chromosome 1212q21.1p13.33p13.32p13.31p13.2p13.1p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11q12q13.11q13.12q13.13q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.31q24.32q24.3371.2 Mb71.4 Mb71.6 Mb71.8 Mb72 MbTSPAN8: 71,124,454–71,441,898, reverse strandTSPAN8LGR5: 71,439,798–71,586,310, forward strandLGR5ZFC3H1: 71,606,412–71,667,725, reverse strandZFC3H1THAP2: 71,663,968–71,680,644, forward strandTHAP2: 71,674,204–71,698,968, forward strandFAABTP: 71,686,063–71,705,047, forward strandFAABTPRAB21: 71,754,835–71,800,286, forward strandRAB21TBC1D15: 71,839,707–71,927,248, forward strandTBC1D15TPH2: 71,938,845–72,186,618, forward strandTPH2Diagram of LGR5: 18 exons on the forward strand of chromosome 12Exon 1: 71,439,798–71,440,292, 495 basesExon 2: 71,504,614–71,504,685, 72 basesExon 3: 71,524,406–71,524,477, 72 basesExon 4: 71,535,115–71,535,186, 72 basesExon 5: 71,553,073–71,553,288, 216 basesExon 6: 71,556,619–71,556,690, 72 basesExon 7: 71,559,586–71,559,654, 69 basesExon 8: 71,561,781–71,561,852, 72 basesExon 9: 71,566,404–71,566,475, 72 basesExon 10: 71,566,632–71,566,700, 69 basesExon 11: 71,566,841–71,566,912, 72 basesExon 12: 71,571,514–71,571,579, 66 basesExon 13: 71,572,850–71,572,921, 72 basesExon 14: 71,577,925–71,577,996, 72 basesExon 15: 71,578,804–71,578,929, 126 basesExon 16: 71,580,278–71,580,423, 146 basesExon 17: 71,582,456–71,582,539, 84 basesExon 18: 71,583,647–71,586,310, 2,664 bases151015185′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.6 kb of the gene's 146.5 kb; 2,724 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). LGR5 gene: leucine rich repeat containing G protein-coupled receptor 5. Retrieved 17 October 2026, from https://dantelabs.com/genes/lgr5

Vancouver

Dante Labs. LGR5 gene: leucine rich repeat containing G protein-coupled receptor 5 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/lgr5

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test