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Gene

KLRK1

killer cell lectin like receptor K1

Summary

Cytogenetic location
12p13.2
Coordinates
Chromosome 12: 10,372,353–10,390,041 (GRCh38)
Exons
8 exons across 17.7 kb
Protein
216 amino acids
Also known as
NKG2D, KLR, NKG2-D, CD314
Previous symbols
D12S2489E
MANE Select transcript
ENST00000240618.11NM_007360.4
Locus type
gene with protein product

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads KLRK1 yet. The test sequences your whole genome, so your data includes it all the same.

How KLRK1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 12, with a bracket where KLRK1 sits. KLRK1 and 29 genes near it on chromosome 12, from 9,881,197 to 10,881,196.Chromosome 1212p13.2p13.33p13.32p13.31p13.2p13.1p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11q12q13.11q13.12q13.13q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.31q24.32q24.3310 Mb10.2 Mb10.4 Mb10.6 Mb10.8 MbKLRF2: 9,881,489–9,895,833, forward strandKLRF2CLEC2A: 9,898,673–9,932,370, reverse strandCLEC2ACLEC12A: 9,951,261–9,996,102, forward strandCLEC12ACLEC1B: 9,985,642–10,013,424, reverse strandCLEC1BCLEC12B: 10,010,627–10,018,802, forward strandCLEC12BCLEC9A: 10,030,678–10,066,031, forward strandCLEC9ACLEC1A: 10,064,397–10,115,555, reverse strandCLEC1ACLEC7A: 10,116,766–10,130,269, reverse strandCLEC7AOLR1: 10,156,240–10,172,143, reverse strandOLR1TMEM52B: 10,170,512–10,191,807, forward strandTMEM52BGABARAPL1: 10,212,458–10,223,132, forward strandGABARAPL1KLRD1: 10,226,058–10,329,608, forward strandKLRD1KLRK1: 10,372,353–10,390,041, reverse strandKLRK1KLRC4-KLRK1: 10,372,353–10,410,146, reverse strandKLRC4-KLRK1KLRC4: 10,403,058–10,409,757, reverse strandKLRC4KLRC3: 10,412,309–10,420,595, reverse strandKLRC3: 10,412,312–10,436,001, reverse strandKLRC2: 10,426,854–10,442,300, reverse strandKLRC1: 10,440,411–10,454,685, reverse strandEIF2S3B: 10,505,602–10,523,135, forward strandEIF2S3BMAGOHB: 10,603,393–10,613,616, reverse strandMAGOHBSTYK1: 10,616,641–10,674,318, reverse strandSTYK1YBX3: 10,693,264–10,723,689, reverse strandYBX3TAS2R7: 10,801,532–10,802,627, reverse strandTAS2R7TAS2R8: 10,806,051–10,807,286, reverse strandTAS2R8TAS2R9: 10,809,094–10,810,168, reverse strandTAS2R9PRH1: 10,824,960–11,171,608, reverse strandTAS2R10: 10,825,219–10,826,358, reverse strandTAS2R10PRR4: 10,845,845–11,171,600, reverse strandPRR4: 10,845,849–11,171,598, reverse strandDiagram of KLRK1: 8 exons on the reverse strand of chromosome 12Exon 8: 10,372,353–10,373,231, 879 basesExon 7: 10,378,132–10,378,235, 104 basesExon 6: 10,378,554–10,378,705, 152 basesExon 5: 10,379,447–10,379,482, 36 basesExon 4: 10,379,700–10,379,792, 93 basesExon 3: 10,386,903–10,387,010, 108 basesExon 2: 10,388,771–10,388,875, 105 basesExon 1: 10,389,943–10,390,041, 99 bases876543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.6 kb of the gene's 17.7 kb; 651 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). KLRK1 gene: killer cell lectin like receptor K1. Retrieved 17 October 2026, from https://dantelabs.com/genes/klrk1

Vancouver

Dante Labs. KLRK1 gene: killer cell lectin like receptor K1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/klrk1

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