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Gene

HTRA4

HtrA serine peptidase 4

Summary

Cytogenetic location
8p11.22
Coordinates
Chromosome 8: 38,974,228–38,988,663 (GRCh38)
Exons
9 exons across 14.4 kb
Protein
476 amino acids
Also known as
FLJ90724
MANE Select transcript
ENST00000302495.5NM_153692.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads HTRA4 yet. The test sequences your whole genome, so your data includes it all the same.

How HTRA4 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 8, with a bracket where HTRA4 sits. HTRA4 and 5 genes near it on chromosome 8, from 38,481,446 to 39,481,445.Chromosome 88p11.22p23.3p23.2p23.1p22p21.3p21.2p21.1p12p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.3q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.338.6 Mb38.8 Mb39 Mb39.2 Mb39.4 MbTACC1: 38,728,157–38,853,028, forward strandTACC1PLEKHA2: 38,901,024–38,973,912, forward strandPLEKHA2HTRA4: 38,974,228–38,988,663, forward strandHTRA4TM2D2: 38,988,808–38,996,824, reverse strandTM2D2ADAM9: 38,996,754–39,105,447, forward strandADAM9ADAM32: 39,106,990–39,284,917, forward strandADAM32Diagram of HTRA4: 9 exons on the forward strand of chromosome 8Exon 1: 38,974,228–38,974,729, 502 basesExon 2: 38,975,031–38,975,130, 100 basesExon 3: 38,976,535–38,976,739, 205 basesExon 4: 38,977,953–38,978,147, 195 basesExon 5: 38,979,215–38,979,247, 33 basesExon 6: 38,981,653–38,981,767, 115 basesExon 7: 38,982,498–38,982,555, 58 basesExon 8: 38,982,953–38,983,048, 96 basesExon 9: 38,987,936–38,988,663, 728 bases1234567895′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2 kb of the gene's 14.4 kb; 1,431 of those bases code for the protein.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). HTRA4 gene: HtrA serine peptidase 4. Retrieved 17 October 2026, from https://dantelabs.com/genes/htra4

Vancouver

Dante Labs. HTRA4 gene: HtrA serine peptidase 4 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/htra4

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