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Gene

HSD17B11

hydroxysteroid 17-beta dehydrogenase 11

Summary

Cytogenetic location
4q22.1
Coordinates
Chromosome 4: 87,336,515–87,391,188 (GRCh38)
Exons
7 exons across 54.7 kb
Protein
300 amino acids
Also known as
RetSDR2, 17-BETA-HSD11, 17-BETA-HSDXI, PAN1B, SDR16C2
Previous symbols
DHRS8
MANE Select transcript
ENST00000358290.9NM_016245.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads HSD17B11 yet. The test sequences your whole genome, so your data includes it all the same.

How HSD17B11 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 4, with a bracket where HSD17B11 sits. HSD17B11 and 12 genes near it on chromosome 4, from 86,863,852 to 87,863,851.Chromosome 44q22.1p16.3p16.2p16.1p15.33p15.32p15.31p15.2p15.1p14p13p12p11q11q12q13.1q13.2q13.3q21.1q21.21q21.22q21.23q21.3q22.1q22.2q22.3q23q24q25q26q27q28.1q28.2q28.3q31.1q31.21q31.22q31.23q31.3q32.1q32.2q32.3q33q34.1q34.2q34.3q35.1q35.287 Mb87.2 Mb87.4 Mb87.6 Mb87.8 MbC4orf36: 86,876,205–86,892,813, reverse strandC4orf36C4orf36: 86,886,472–86,936,178, reverse strandC4orf36AFF1: 86,934,203–87,141,073, forward strandAFF1KLHL8: 87,159,883–87,240,729, reverse strandKLHL8HSD17B13: 87,301,953–87,322,948, reverse strandHSD17B13HSD17B11: 87,336,515–87,391,188, reverse strandHSD17B11NUDT9: 87,422,573–87,459,455, forward strandNUDT9SCPPPQ1: 87,460,802–87,471,050, reverse strandSCPPPQ1SPARCL1: 87,473,329–87,531,118, reverse strandSPARCL1DSPP: 87,608,529–87,616,873, forward strandDSPPDMP1: 87,650,278–87,664,361, forward strandDMP1IBSP: 87,799,546–87,813,329, forward strandIBSPMEPE: 87,821,398–87,846,814, forward strandMEPEDiagram of HSD17B11: 7 exons on the reverse strand of chromosome 4Exon 7: 87,336,515–87,337,366, 852 basesExon 6: 87,340,490–87,340,606, 117 basesExon 5: 87,357,279–87,357,416, 138 basesExon 4: 87,372,709–87,372,815, 107 basesExon 3: 87,374,699–87,374,830, 132 basesExon 2: 87,382,255–87,382,362, 108 basesExon 1: 87,390,861–87,391,188, 328 bases76543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.8 kb of the gene's 54.7 kb; 903 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). HSD17B11 gene: hydroxysteroid 17-beta dehydrogenase 11. Retrieved 17 October 2026, from https://dantelabs.com/genes/hsd17b11

Vancouver

Dante Labs. HSD17B11 gene: hydroxysteroid 17-beta dehydrogenase 11 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/hsd17b11

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