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Gene

HELB

DNA helicase B

Summary

Cytogenetic location
12q14.3
Coordinates
Chromosome 12: 66,302,493–66,338,199 (GRCh38)
Exons
13 exons across 35.7 kb
Protein
1,087 amino acids
MANE Select transcript
ENST00000247815.9NM_001370285.1
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads HELB yet. The test sequences your whole genome, so your data includes it all the same.

How HELB is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 12, with a bracket where HELB sits. HELB and 6 genes near it on chromosome 12, from 65,820,346 to 66,820,345.Chromosome 1212q14.3p13.33p13.32p13.31p13.2p13.1p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11q12q13.11q13.12q13.13q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.31q24.32q24.3366 Mb66.2 Mb66.4 Mb66.6 Mb66.8 MbHMGA2: 65,824,224–65,966,291, forward strandHMGA2LLPH: 66,114,523–66,130,761, reverse strandLLPH: 66,123,917–66,169,985, reverse strandTMBIM4: 66,135,846–66,170,074, reverse strandTMBIM4IRAK3: 66,188,995–66,254,622, forward strandIRAK3HELB: 66,302,493–66,338,199, forward strandHELBGRIP1: 66,347,431–67,069,162, reverse strandGRIP1Diagram of HELB: 13 exons on the forward strand of chromosome 12Exon 1: 66,302,493–66,302,790, 298 basesExon 2: 66,304,731–66,305,150, 420 basesExon 3: 66,306,345–66,306,514, 170 basesExon 4: 66,309,706–66,310,608, 903 basesExon 5: 66,313,986–66,314,163, 178 basesExon 6: 66,315,242–66,315,383, 142 basesExon 7: 66,318,638–66,318,792, 155 basesExon 8: 66,321,948–66,322,029, 82 basesExon 9: 66,322,724–66,322,783, 60 basesExon 10: 66,323,983–66,324,211, 229 basesExon 11: 66,324,983–66,325,126, 144 basesExon 12: 66,331,154–66,331,645, 492 basesExon 13: 66,338,001–66,338,199, 199 bases123456789101112135′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.5 kb of the gene's 35.7 kb; 3,264 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). HELB gene: DNA helicase B. Retrieved 17 October 2026, from https://dantelabs.com/genes/helb

Vancouver

Dante Labs. HELB gene: DNA helicase B [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/helb

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