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Gene

HACL1

2-hydroxyacyl-CoA lyase 1

Summary

Cytogenetic location
3p25.1
Coordinates
Chromosome 3: 15,560,699–15,601,569 (GRCh38)
Exons
17 exons across 40.9 kb
Protein
578 amino acids
Also known as
2-HPCL, PHYH2
Previous symbols
HPCL
MANE Select transcript
ENST00000321169.10NM_012260.4
Locus type
gene with protein product

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads HACL1 yet. The test sequences your whole genome, so your data includes it all the same.

How HACL1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 3, with a bracket where HACL1 sits. HACL1 and 9 genes near it on chromosome 3, from 15,081,134 to 16,081,133.Chromosome 33p25.1p26.3p26.2p26.1p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13.11q13.12q13.13q13.2q13.31q13.32q13.33q21.1q21.2q21.3q22.1q22.2q22.3q23q24q25.1q25.2q25.31q25.32q25.33q26.1q26.2q26.31q26.32q26.33q27.1q27.2q27.3q28q2915.2 Mb15.4 Mb15.6 Mb15.8 Mb16 MbRBSN: 15,068,565–15,099,163, reverse strandRBSNCAPN7: 15,206,112–15,254,068, forward strandCAPN7SH3BP5: 15,254,254–15,341,368, reverse strandSH3BP5METTL6: 15,381,061–15,440,566, reverse strandMETTL6EAF1: 15,427,552–15,450,635, forward strandEAF1: 15,439,199–15,455,940, reverse strandCOLQ: 15,450,132–15,521,928, reverse strandCOLQHACL1: 15,560,699–15,601,569, reverse strandHACL1BTD: 15,601,341–15,722,522, forward strandBTDANKRD28: 15,667,131–15,859,847, reverse strandANKRD28Diagram of HACL1: 17 exons on the reverse strand of chromosome 3Exon 17: 15,560,699–15,560,897, 199 basesExon 16: 15,563,358–15,563,544, 187 basesExon 15: 15,564,551–15,564,658, 108 basesExon 14: 15,567,844–15,568,002, 159 basesExon 13: 15,568,432–15,568,586, 155 basesExon 12: 15,571,668–15,571,769, 102 basesExon 11: 15,573,159–15,573,242, 84 basesExon 10: 15,574,977–15,575,082, 106 basesExon 9: 15,579,910–15,580,045, 136 basesExon 8: 15,582,877–15,582,989, 113 basesExon 7: 15,585,248–15,585,342, 95 basesExon 6: 15,586,525–15,586,602, 78 basesExon 5: 15,589,540–15,589,612, 73 basesExon 4: 15,591,600–15,591,680, 81 basesExon 3: 15,596,384–15,596,424, 41 basesExon 2: 15,601,090–15,601,194, 105 basesExon 1: 15,601,383–15,601,569, 187 bases171510515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2 kb of the gene's 40.9 kb; 1,737 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). HACL1 gene: 2-hydroxyacyl-CoA lyase 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/hacl1

Vancouver

Dante Labs. HACL1 gene: 2-hydroxyacyl-CoA lyase 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/hacl1

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