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Gene

GEN1

GEN1 structure-specific endonuclease

Summary

Cytogenetic location
2p24.2
Coordinates
Chromosome 2: 17,754,138–17,788,946 (GRCh38)
Exons
14 exons across 34.8 kb
Protein
908 amino acids
Also known as
FLJ40869, Gen
MANE Select transcript
ENST00000381254.7NM_001130009.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads GEN1 yet. The test sequences your whole genome, so your data includes it all the same.

How GEN1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 2, with a bracket where GEN1 sits. GEN1 and 5 genes near it on chromosome 2, from 17,271,542 to 18,271,541.Chromosome 22p24.2p25.3p25.2p25.1p24.3p24.2p24.1p23.3p23.2p23.1p22.3p22.2p22.1p21p16.3p16.2p16.1p15p14p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13q14.1q14.2q14.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.1q32.2q32.3q33.1q33.2q33.3q34q35q36.1q36.2q36.3q37.1q37.2q37.317.4 Mb17.6 Mb17.8 Mb18 Mb18.2 MbRAD51AP2: 17,510,159–17,518,440, reverse strandRAD51AP2VSNL1: 17,539,020–17,657,624, forward strandVSNL1SMC6: 17,662,940–17,800,242, reverse strandSMC6GEN1: 17,754,138–17,788,946, forward strandGEN1MSGN1: 17,816,460–17,817,798, forward strandMSGN1KCNS3: 17,877,847–18,361,616, forward strandKCNS3Diagram of GEN1: 14 exons on the forward strand of chromosome 2Exon 1: 17,754,138–17,754,345, 208 basesExon 2: 17,759,929–17,760,104, 176 basesExon 3: 17,761,396–17,761,582, 187 basesExon 4: 17,764,897–17,765,073, 177 basesExon 5: 17,766,579–17,766,689, 111 basesExon 6: 17,768,738–17,768,811, 74 basesExon 7: 17,771,196–17,771,287, 92 basesExon 8: 17,772,634–17,772,784, 151 basesExon 9: 17,773,096–17,773,132, 37 basesExon 10: 17,773,219–17,773,299, 81 basesExon 11: 17,774,271–17,774,401, 131 basesExon 12: 17,778,002–17,778,063, 62 basesExon 13: 17,779,978–17,780,121, 144 basesExon 14: 17,780,621–17,788,946, 8,326 bases1510145′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 10 kb of the gene's 34.8 kb; 2,727 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). GEN1 gene: GEN1 structure-specific endonuclease. Retrieved 17 October 2026, from https://dantelabs.com/genes/gen1

Vancouver

Dante Labs. GEN1 gene: GEN1 structure-specific endonuclease [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/gen1

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