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Gene

GABPA

GA binding protein transcription factor subunit alpha

Summary

Cytogenetic location
21q21.3
Coordinates
Chromosome 21: 25,734,972–25,772,460 (GRCh38)
Exons
10 exons across 37.5 kb
Protein
454 amino acids
Also known as
E4TF1A, NFT2, NRF2, E4TF1-60, NRF2A
MANE Select transcript
ENST00000400075.4NM_002040.4
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads GABPA yet. The test sequences your whole genome, so your data includes it all the same.

How GABPA is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 21, with a bracket where GABPA sits. GABPA and 4 genes near it on chromosome 21, from 25,253,716 to 26,253,715.Chromosome 2121q21.3p13p12p11.2p11.1q11.1q11.2q21.1q21.2q21.3q22.11q22.12q22.13q22.2q22.325.4 Mb25.6 Mb25.8 Mb26 Mb26.2 MbMRPL39: 25,572,145–25,607,588, reverse strandMRPL39JAM2: 25,639,258–25,717,783, forward strandJAM2ATP5PF: 25,693,623–25,735,721, reverse strandATP5PFGABPA: 25,734,972–25,772,460, forward strandGABPAAPP: 25,880,535–26,171,128, reverse strandAPPDiagram of GABPA: 10 exons on the forward strand of chromosome 21Exon 1: 25,734,972–25,735,578, 607 basesExon 2: 25,741,573–25,741,675, 103 basesExon 3: 25,745,210–25,745,354, 145 basesExon 4: 25,749,036–25,749,120, 85 basesExon 5: 25,751,989–25,752,234, 246 basesExon 6: 25,758,010–25,758,204, 195 basesExon 7: 25,762,312–25,762,365, 54 basesExon 8: 25,764,210–25,764,350, 141 basesExon 9: 25,764,595–25,764,787, 193 basesExon 10: 25,769,004–25,772,460, 3,457 bases12468105′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.2 kb of the gene's 37.5 kb; 1,365 of those bases code for the protein.

Sequencing GABPA

40High

How hard GABPA is to sequence with short reads, out of 100

  • Mappability50%
  • Homology66%
  • Repeats3.1%
  • GC content22%
  • Reference coverage0%

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Genome in a Bottle genome stratifications, from NIST: the sequencing difficulty score.

Cite this page

APA

Dante Labs. (n.d.). GABPA gene: GA binding protein transcription factor subunit alpha. Retrieved 17 October 2026, from https://dantelabs.com/genes/gabpa

Vancouver

Dante Labs. GABPA gene: GA binding protein transcription factor subunit alpha [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/gabpa

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