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Gene

FAP

fibroblast activation protein alpha

Summary

Cytogenetic location
2q24.2
Coordinates
Chromosome 2: 162,170,684–162,243,445 (GRCh38)
Exons
26 exons across 72.8 kb
Protein
760 amino acids
Also known as
DPPIV
MANE Select transcript
ENST00000188790.9NM_004460.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads FAP yet. The test sequences your whole genome, so your data includes it all the same.

How FAP is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 2, with a bracket where FAP sits. FAP and 6 genes near it on chromosome 2, from 161,707,065 to 162,707,064.Chromosome 22q24.2p25.3p25.2p25.1p24.3p24.2p24.1p23.3p23.2p23.1p22.3p22.2p22.1p21p16.3p16.2p16.1p15p14p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13q14.1q14.2q14.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.1q32.2q32.3q33.1q33.2q33.3q34q35q36.1q36.2q36.3q37.1q37.2q37.3161.8 Mb162 Mb162.2 Mb162.4 Mb162.6 MbSLC4A10: 161,424,332–161,985,329, forward strandSLC4A10DPP4: 161,992,243–162,074,639, reverse strandDPP4GCG: 162,142,877–162,152,404, reverse strandGCGFAP: 162,170,684–162,243,445, reverse strandFAPIFIH1: 162,267,074–162,318,684, reverse strandIFIH1GCA: 162,318,839–162,388,536, forward strandGCAKCNH7: 162,365,721–162,838,791, reverse strandKCNH7Diagram of FAP: 26 exons on the reverse strand of chromosome 2Exon 26: 162,170,684–162,171,080, 397 basesExon 25: 162,172,811–162,172,884, 74 basesExon 24: 162,173,149–162,173,221, 73 basesExon 23: 162,173,723–162,173,787, 65 basesExon 22: 162,174,867–162,174,966, 100 basesExon 21: 162,183,414–162,183,468, 55 basesExon 20: 162,188,169–162,188,363, 195 basesExon 19: 162,189,103–162,189,172, 70 basesExon 18: 162,189,656–162,189,754, 99 basesExon 17: 162,194,701–162,194,748, 48 basesExon 16: 162,198,757–162,198,881, 125 basesExon 15: 162,200,566–162,200,619, 54 basesExon 14: 162,202,872–162,202,942, 71 basesExon 13: 162,203,041–162,203,145, 105 basesExon 12: 162,209,952–162,209,996, 45 basesExon 11: 162,213,938–162,214,073, 136 basesExon 10: 162,215,898–162,216,001, 104 basesExon 9: 162,217,986–162,218,140, 155 basesExon 8: 162,219,063–162,219,183, 121 basesExon 7: 162,219,853–162,219,925, 73 basesExon 6: 162,223,608–162,223,660, 53 basesExon 5: 162,224,466–162,224,540, 75 basesExon 4: 162,225,483–162,225,577, 95 basesExon 3: 162,226,523–162,226,621, 99 basesExon 2: 162,242,908–162,242,992, 85 basesExon 1: 162,243,322–162,243,445, 124 bases2625201510515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.7 kb of the gene's 72.8 kb; 2,283 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). FAP gene: fibroblast activation protein alpha. Retrieved 17 October 2026, from https://dantelabs.com/genes/fap

Vancouver

Dante Labs. FAP gene: fibroblast activation protein alpha [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/fap

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