Skip to content
Use your HSA or FSA funds

Gene

EPS15

epidermal growth factor receptor pathway substrate 15

Summary

Cytogenetic location
1p32.3
Coordinates
Chromosome 1: 51,354,263–51,519,266 (GRCh38)
Exons
25 exons across 165 kb
Protein
896 amino acids
Also known as
AF-1P, MLLT5
MANE Select transcript
ENST00000371733.8NM_001981.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads EPS15 yet. The test sequences your whole genome, so your data includes it all the same.

How EPS15 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 1, with a bracket where EPS15 sits. EPS15 and 8 genes near it on chromosome 1, from 50,936,765 to 51,936,764.Chromosome 11p32.3p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q4451 Mb51.2 Mb51.4 Mb51.6 Mb51.8 MbFAF1: 50,437,028–50,960,288, reverse strandFAF1CDKN2C: 50,960,745–50,975,654, forward strandCDKN2CC1orf185: 51,102,221–51,148,086, forward strandC1orf185RNF11: 51,235,625–51,289,232, forward strandRNF11TTC39A: 51,286,312–51,345,121, reverse strandTTC39AEPS15: 51,354,263–51,519,266, reverse strandEPS15OSBPL9: 51,577,179–51,798,427, forward strandOSBPL9NRDC: 51,787,517–51,878,811, reverse strandNRDCRAB3B: 51,907,956–51,990,746, reverse strandRAB3BDiagram of EPS15: 25 exons on the reverse strand of chromosome 1Exon 25: 51,354,263–51,356,846, 2,584 basesExon 24: 51,361,171–51,361,355, 185 basesExon 23: 51,363,866–51,364,028, 163 basesExon 22: 51,365,953–51,366,029, 77 basesExon 21: 51,394,381–51,394,447, 67 basesExon 20: 51,399,032–51,399,165, 134 basesExon 19: 51,400,918–51,400,953, 36 basesExon 18: 51,402,435–51,402,525, 91 basesExon 17: 51,403,419–51,403,532, 114 basesExon 16: 51,405,905–51,406,108, 204 basesExon 15: 51,408,135–51,408,332, 198 basesExon 14: 51,409,535–51,409,696, 162 basesExon 13: 51,421,786–51,421,858, 73 basesExon 12: 51,440,347–51,440,432, 86 basesExon 11: 51,444,889–51,445,045, 157 basesExon 10: 51,446,960–51,447,105, 146 basesExon 9: 51,448,046–51,448,135, 90 basesExon 8: 51,461,091–51,461,150, 60 basesExon 7: 51,463,673–51,463,798, 126 basesExon 6: 51,465,261–51,465,326, 66 basesExon 5: 51,468,473–51,468,568, 96 basesExon 4: 51,471,690–51,471,737, 48 basesExon 3: 51,472,859–51,472,948, 90 basesExon 2: 51,481,273–51,481,314, 42 basesExon 1: 51,519,199–51,519,266, 68 bases25201510515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.2 kb of the gene's 165 kb; 2,691 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). EPS15 gene: epidermal growth factor receptor pathway substrate 15. Retrieved 17 October 2026, from https://dantelabs.com/genes/eps15

Vancouver

Dante Labs. EPS15 gene: epidermal growth factor receptor pathway substrate 15 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/eps15

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test