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Gene

DUOX1

dual oxidase 1

Summary

Cytogenetic location
15q21.1
Coordinates
Chromosome 15: 45,129,994–45,165,574 (GRCh38)
Exons
34 exons across 35.6 kb
Protein
1,551 amino acids
Also known as
NOXEF1, THOX1, LNOX1
MANE Select transcript
ENST00000389037.7NM_175940.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads DUOX1 yet. The test sequences your whole genome, so your data includes it all the same.

How DUOX1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 15, with a bracket where DUOX1 sits. DUOX1 and 18 genes near it on chromosome 15, from 44,647,784 to 45,647,783.Chromosome 1515q21.1p13p12p11.2p11.1q11.1q11.2q12q13.1q13.2q13.3q14q15.1q15.2q15.3q21.1q21.2q21.3q22.1q22.2q22.31q22.32q22.33q23q24.1q24.2q24.3q25.1q25.2q25.3q26.1q26.2q26.344.8 Mb45 Mb45.2 Mb45.4 Mb45.6 MbSPG11: 44,554,436–44,663,688, reverse strandSPG11PATL2: 44,665,723–44,711,384, reverse strandPATL2B2M: 44,711,253–44,718,851, forward strandB2MTRIM69: 44,728,986–44,767,829, forward strandTRIM69TERB2: 44,956,687–44,979,229, forward strandTERB2SORD: 45,023,116–45,077,185, forward strandSORDDUOX2: 45,092,650–45,114,185, reverse strandDUOX2DUOXA2: 45,114,325–45,118,421, forward strandDUOXA2DUOXA1: 45,117,364–45,130,611, reverse strandDUOXA1DUOX1: 45,129,994–45,165,574, forward strandDUOX1SHF: 45,165,572–45,201,175, reverse strandSHFSLC28A2: 45,252,227–45,277,846, forward strandSLC28A2GATM: 45,333,479–45,402,327, reverse strandGATMAFG2B: 45,402,325–45,421,415, forward strandAFG2BCOXFA4L3: 45,430,579–45,448,761, forward strandCOXFA4L3SLC30A4: 45,479,606–45,522,834, reverse strandSLC30A4BLOC1S6: 45,587,108–45,615,945, forward strandBLOC1S6: 45,587,351–45,676,314, forward strandSQOR: 45,631,148–45,691,299, forward strandSQORDiagram of DUOX1: 34 exons on the forward strand of chromosome 15Exon 1: 45,129,994–45,130,098, 105 basesExon 2: 45,131,918–45,132,024, 107 basesExon 3: 45,133,864–45,133,947, 84 basesExon 4: 45,134,145–45,134,309, 165 basesExon 5: 45,135,104–45,135,291, 188 basesExon 6: 45,135,474–45,135,675, 202 basesExon 7: 45,135,782–45,135,948, 167 basesExon 8: 45,136,350–45,136,410, 61 basesExon 9: 45,136,529–45,136,625, 97 basesExon 10: 45,137,924–45,138,014, 91 basesExon 11: 45,139,066–45,139,168, 103 basesExon 12: 45,139,427–45,139,599, 173 basesExon 13: 45,140,895–45,141,070, 176 basesExon 14: 45,141,292–45,141,410, 119 basesExon 15: 45,141,975–45,142,112, 138 basesExon 16: 45,143,190–45,143,303, 114 basesExon 17: 45,144,036–45,144,235, 200 basesExon 18: 45,144,895–45,145,080, 186 basesExon 19: 45,147,433–45,147,658, 226 basesExon 20: 45,147,904–45,147,997, 94 basesExon 21: 45,148,272–45,148,447, 176 basesExon 22: 45,150,632–45,150,701, 70 basesExon 23: 45,151,123–45,151,248, 126 basesExon 24: 45,151,874–45,152,052, 179 basesExon 25: 45,152,286–45,152,516, 231 basesExon 26: 45,153,380–45,153,479, 100 basesExon 27: 45,153,951–45,154,000, 50 basesExon 28: 45,155,802–45,155,929, 128 basesExon 29: 45,160,837–45,160,990, 154 basesExon 30: 45,161,738–45,161,970, 233 basesExon 31: 45,162,219–45,162,377, 159 basesExon 32: 45,163,532–45,163,687, 156 basesExon 33: 45,163,790–45,163,918, 129 basesExon 34: 45,164,779–45,165,574, 796 bases12468101214161820222426283032345′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.5 kb of the gene's 35.6 kb; 4,656 of those bases code for the protein.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). DUOX1 gene: dual oxidase 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/duox1

Vancouver

Dante Labs. DUOX1 gene: dual oxidase 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/duox1

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