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Gene

DROSHA

drosha ribonuclease III

Summary

Cytogenetic location
5p13.3
Coordinates
Chromosome 5: 31,400,494–31,532,093 (GRCh38)
Exons
36 exons across 131.6 kb
Protein
1,374 amino acids
Also known as
RNASE3L, Etohi2, HSA242976, RN3
Previous symbols
RNASEN
MANE Select transcript
ENST00000344624.8NM_001382508.1
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads DROSHA yet. The test sequences your whole genome, so your data includes it all the same.

How DROSHA is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 5, with a bracket where DROSHA sits. DROSHA and 3 genes near it on chromosome 5, from 30,966,294 to 31,966,293.Chromosome 55p13.3p15.33p15.32p15.31p15.2p15.1p14.3p14.2p14.1p13.3p13.2p13.1p12p11q11.1q11.2q12.1q12.2q12.3q13.1q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q31.1q31.2q31.3q32q33.1q33.2q33.3q34q35.1q35.2q35.331 Mb31.2 Mb31.4 Mb31.6 Mb31.8 MbCDH6: 31,193,679–31,329,146, forward strandCDH6DROSHA: 31,400,494–31,532,093, reverse strandDROSHAC5orf22: 31,532,278–31,555,335, forward strandC5orf22PDZD2: 31,638,965–32,110,933, forward strandPDZD2Diagram of DROSHA: 36 exons on the reverse strand of chromosome 5Exon 36: 31,400,494–31,401,562, 1,069 basesExon 35: 31,405,677–31,405,723, 47 basesExon 34: 31,406,853–31,406,945, 93 basesExon 33: 31,409,056–31,409,159, 104 basesExon 32: 31,409,250–31,409,332, 83 basesExon 31: 31,410,746–31,410,887, 142 basesExon 30: 31,421,272–31,421,377, 106 basesExon 29: 31,422,787–31,422,944, 158 basesExon 28: 31,424,427–31,424,471, 45 basesExon 27: 31,429,475–31,429,545, 71 basesExon 26: 31,431,576–31,431,678, 103 basesExon 25: 31,435,765–31,435,864, 100 basesExon 24: 31,437,239–31,437,298, 60 basesExon 23: 31,448,547–31,448,607, 61 basesExon 22: 31,449,281–31,449,419, 139 basesExon 21: 31,451,533–31,451,640, 108 basesExon 20: 31,464,236–31,464,343, 108 basesExon 19: 31,466,182–31,466,281, 100 basesExon 18: 31,467,939–31,468,063, 125 basesExon 17: 31,472,063–31,472,232, 170 basesExon 16: 31,483,554–31,483,628, 75 basesExon 15: 31,484,881–31,484,962, 82 basesExon 14: 31,486,491–31,486,562, 72 basesExon 13: 31,493,207–31,493,293, 87 basesExon 12: 31,495,286–31,495,372, 87 basesExon 11: 31,504,555–31,504,635, 81 basesExon 10: 31,508,621–31,508,775, 155 basesExon 9: 31,511,035–31,511,176, 142 basesExon 8: 31,514,988–31,515,219, 232 basesExon 7: 31,515,454–31,515,564, 111 basesExon 6: 31,521,123–31,521,215, 93 basesExon 5: 31,526,079–31,526,912, 834 basesExon 4: 31,529,040–31,529,105, 66 basesExon 3: 31,530,798–31,530,924, 127 basesExon 2: 31,531,450–31,531,525, 76 basesExon 1: 31,531,990–31,532,093, 104 bases36353025201510515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.4 kb of the gene's 131.6 kb; 4,125 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). DROSHA gene: drosha ribonuclease III. Retrieved 17 October 2026, from https://dantelabs.com/genes/drosha

Vancouver

Dante Labs. DROSHA gene: drosha ribonuclease III [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/drosha

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