Skip to content
Use your HSA or FSA funds
Sequence your genome (opens in a new tab)

Gene

ASTL

astacin like metalloendopeptidase

Summary

Cytogenetic location
2q11.2
Coordinates
Chromosome 2: 96,122,818–96,138,502 (GRCh38)
Exons
9 exons across 15.7 kb
Protein
431 amino acids
Also known as
ovastacin, SAS1B
MANE Select transcript
ENST00000342380.3NM_001002036.4
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads ASTL yet. The test sequences your whole genome, so your data includes it all the same.

How ASTL is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 2, with a bracket where ASTL sits. ASTL and 13 genes near it on chromosome 2, from 95,630,660 to 96,630,659.Chromosome 22q11.2p25.3p25.2p25.1p24.3p24.2p24.1p23.3p23.2p23.1p22.3p22.2p22.1p21p16.3p16.2p16.1p15p14p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13q14.1q14.2q14.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.1q32.2q32.3q33.1q33.2q33.3q34q35q36.1q36.2q36.3q37.1q37.2q37.395.8 Mb96 Mb96.2 Mb96.4 Mb96.6 MbANKRD36C: 95,836,919–95,991,843, reverse strandANKRD36CGPAT2: 96,021,943–96,039,451, reverse strandGPAT2ADRA2B: 96,112,876–96,116,571, reverse strandADRA2BASTL: 96,122,818–96,138,502, reverse strandASTLDUSP2: 96,143,166–96,145,447, reverse strandDUSP2STARD7: 96,184,859–96,208,854, reverse strandSTARD7TMEM127: 96,248,500–96,266,082, reverse strandTMEM127CIAO1: 96,266,159–96,274,173, forward strandCIAO1SNRNP200: 96,274,336–96,321,271, reverse strandSNRNP200ITPRIPL1: 96,324,977–96,330,517, forward strandITPRIPL1NCAPH: 96,335,728–96,377,091, forward strandNCAPHNEURL3: 96,497,644–96,508,153, reverse strandNEURL3ARID5A: 96,536,699–96,552,639, forward strandARID5AKANSL3: 96,584,179–96,642,787, reverse strandKANSL3Diagram of ASTL: 9 exons on the reverse strand of chromosome 2Exon 9: 96,122,818–96,124,271, 1,454 basesExon 8: 96,129,824–96,129,978, 155 basesExon 7: 96,130,064–96,130,145, 82 basesExon 6: 96,132,540–96,132,721, 182 basesExon 5: 96,133,425–96,133,542, 118 basesExon 4: 96,133,965–96,134,058, 94 basesExon 3: 96,135,351–96,135,412, 62 basesExon 2: 96,137,575–96,137,700, 126 basesExon 1: 96,138,382–96,138,502, 121 bases9864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.4 kb of the gene's 15.7 kb; 1,296 of those bases code for the protein.

Traits linked to ASTL

The Human Phenotype Ontology lists these as features of the rare conditions ASTL can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). ASTL gene: astacin like metalloendopeptidase. Retrieved 17 October 2026, from https://dantelabs.com/genes/astl

Vancouver

Dante Labs. ASTL gene: astacin like metalloendopeptidase [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/astl

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test