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Gene

ARHGEF28

Rho guanine nucleotide exchange factor 28

Summary

Cytogenetic location
5q13.2
Coordinates
Chromosome 5: 73,626,196–73,941,990 (GRCh38)
Exons
36 exons across 315.8 kb
Protein
1,705 amino acids
Also known as
RGNEF, p190RhoGEF, RIP2
MANE Select transcript
ENST00000513042.7NM_001177693.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads ARHGEF28 yet. The test sequences your whole genome, so your data includes it all the same.

How ARHGEF28 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 5, with a bracket where ARHGEF28 sits. ARHGEF28 and 4 genes near it on chromosome 5, from 73,284,093 to 74,284,092.Chromosome 55q13.2p15.33p15.32p15.31p15.2p15.1p14.3p14.2p14.1p13.3p13.2p13.1p12p11q11.1q11.2q12.1q12.2q12.3q13.1q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q31.1q31.2q31.3q32q33.1q33.2q33.3q34q35.1q35.2q35.373.4 Mb73.6 Mb73.8 Mb74 Mb74.2 MbFOXD1: 73,444,827–73,448,777, reverse strandFOXD1BTF3: 73,498,408–73,507,479, forward strandBTF3ANKRA2: 73,552,190–73,565,712, reverse strandANKRA2UTP15: 73,565,443–73,583,380, forward strandUTP15ARHGEF28: 73,626,196–73,941,990, forward strandARHGEF28Diagram of ARHGEF28: 36 exons on the forward strand of chromosome 5Exon 1: 73,626,196–73,626,322, 127 basesExon 2: 73,684,841–73,684,884, 44 basesExon 3: 73,749,837–73,749,984, 148 basesExon 4: 73,752,909–73,753,202, 294 basesExon 5: 73,773,855–73,774,038, 184 basesExon 6: 73,776,516–73,776,696, 181 basesExon 7: 73,780,676–73,780,745, 70 basesExon 8: 73,794,402–73,794,454, 53 basesExon 9: 73,795,331–73,795,391, 61 basesExon 10: 73,832,338–73,832,459, 122 basesExon 11: 73,840,480–73,840,760, 281 basesExon 12: 73,846,268–73,846,475, 208 basesExon 13: 73,848,976–73,849,087, 112 basesExon 14: 73,852,650–73,852,692, 43 basesExon 15: 73,857,656–73,857,779, 124 basesExon 16: 73,858,087–73,858,219, 133 basesExon 17: 73,864,817–73,864,872, 56 basesExon 18: 73,865,965–73,866,013, 49 basesExon 19: 73,867,876–73,868,020, 145 basesExon 20: 73,868,100–73,868,227, 128 basesExon 21: 73,870,069–73,870,209, 141 basesExon 22: 73,872,999–73,873,246, 248 basesExon 23: 73,882,472–73,882,594, 123 basesExon 24: 73,883,767–73,883,884, 118 basesExon 25: 73,885,850–73,886,104, 255 basesExon 26: 73,887,603–73,887,679, 77 basesExon 27: 73,892,052–73,892,230, 179 basesExon 28: 73,893,197–73,893,288, 92 basesExon 29: 73,894,393–73,894,575, 183 basesExon 30: 73,897,962–73,898,093, 132 basesExon 31: 73,901,184–73,901,284, 101 basesExon 32: 73,904,222–73,904,260, 39 basesExon 33: 73,904,358–73,904,405, 48 basesExon 34: 73,909,412–73,909,897, 486 basesExon 35: 73,911,275–73,911,575, 301 basesExon 36: 73,940,844–73,941,990, 1,147 bases15101520253035365′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 6.2 kb of the gene's 315.8 kb; 5,118 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). ARHGEF28 gene: Rho guanine nucleotide exchange factor 28. Retrieved 17 October 2026, from https://dantelabs.com/genes/arhgef28

Vancouver

Dante Labs. ARHGEF28 gene: Rho guanine nucleotide exchange factor 28 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/arhgef28

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