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Gene

ADAMTS5

ADAM metallopeptidase with thrombospondin type 1 motif 5

Summary

Cytogenetic location
21q21.3
Coordinates
Chromosome 21: 26,917,922–26,967,088 (GRCh38)
Exons
8 exons across 49.2 kb
Protein
930 amino acids
Also known as
ADMP-2, ADAMTS11
MANE Select transcript
ENST00000284987.6NM_007038.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads ADAMTS5 yet. The test sequences your whole genome, so your data includes it all the same.

How ADAMTS5 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 21, with a bracket where ADAMTS5 sits. ADAMTS5 and 2 genes near it on chromosome 21, from 26,442,505 to 27,442,504.Chromosome 2121q21.3p13p12p11.2p11.1q11.1q11.2q21.1q21.2q21.3q22.11q22.12q22.13q22.2q22.326.6 Mb26.8 Mb27 Mb27.2 Mb27.4 MbCYYR1: 26,466,209–26,573,314, reverse strandCYYR1ADAMTS1: 26,835,687–26,845,409, reverse strandADAMTS1ADAMTS5: 26,917,922–26,967,088, reverse strandADAMTS5Diagram of ADAMTS5: 8 exons on the reverse strand of chromosome 21Exon 8: 26,917,922–26,924,620, 6,699 basesExon 7: 26,929,886–26,930,061, 176 basesExon 6: 26,932,004–26,932,179, 176 basesExon 5: 26,932,861–26,933,044, 184 basesExon 4: 26,934,466–26,934,749, 284 basesExon 3: 26,943,380–26,943,547, 168 basesExon 2: 26,954,739–26,954,871, 133 basesExon 1: 26,965,288–26,967,088, 1,801 bases876543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 9.6 kb of the gene's 49.2 kb; 2,793 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). ADAMTS5 gene: ADAM metallopeptidase with thrombospondin type 1 motif 5. Retrieved 16 October 2026, from https://dantelabs.com/genes/adamts5

Vancouver

Dante Labs. ADAMTS5 gene: ADAM metallopeptidase with thrombospondin type 1 motif 5 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/adamts5

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