Every MTHFR variant.
Plus your entire genome.
Consumer tests check a few MTHFR variants. Whole genome sequencing reads your entire DNA — including every MTHFR variant, plus 200+ additional reports your doctor can act on.
A lifetime of clinical insights from a single test.
Get actionable genetic reports. User friendly portal organized by clinical area. 30X Genome Test. Full data ownership and privacy protection.
200+ Physician-Ready Reports
Comprehensive reporting across cardiology, oncology, rare disease, neurological conditions, and pharmacogenomics — designed to share directly with your specialist, and continually updated for life as science advances.
Secure Genome Manager
A HIPAA and GDPR-compliant portal with lifelong access to your complete clinical insights, new report releases as science advances, and specialist referral guidance.
30X Clinical Sequencing
Your entire genome sequenced at 30X coverage — the standard required for clinical-grade diagnosis. Every one of your 6.4 billion letters, read.
Full Data Ownership & Privacy
Unrestricted access to your BAM, VCF, and FASTQ files. Your genetic data belongs to you — export it to any independent specialist, at any time, forever.
Dante's secure data architecture was built across multiple, independent GDPR and HIPAA-compliant data protection layers. Your data is never shared with insurers, pharmaceutical companies, or research programs without your explicit consent. You can request deletion at any time.
Full data and privacy policy →Standard genetic tests miss 99.98% of your DNA. Dante reads all of it — so nothing clinically relevant goes unseen.
Four steps to get started.
No clinic visit required.
Order your kit
Ships within 2 business days. Free delivery worldwide.
Collect your sample
Simple saliva collection at home. Takes 5 minutes. Everything you need is in the kit.
Send it back
Pre-paid return label included. Drop it in any post box.
Access your results
Reports delivered to your Genome Manager in 6–8 weeks. Review every finding, ask questions, and share directly with your physician. Your data is stored permanently.
The results doctors bring to their hardest cases.
"You save lives." — Dante Labs customer
Forty years of uncertainty. One test.
A patient had spent decades in the UK healthcare system without a diagnosis. Dante data, accepted by NHS clinical teams at Queen Elizabeth University Hospital Glasgow, identified Noonan Syndrome and a RUNX1 leukemia-associated variant that had gone undetected. After 40 years, they finally had an answer.
A complete read delivers a complete picture.
A patient came to Dante to investigate periodic paralysis. Reading the complete genome identified a concurrent hereditary cardiac finding — Brugada syndrome — that their doctor confirmed with an ECG. The result also explained a family member's unresolved cardiac history. One test. Every answer in it.
Sequenced in 2019. The data worked in 2021.
Jennifer sequenced her genome with Dante two years before her breast cancer diagnosis. When treatment began, Dante's pharmacogenomics data showed her prescribed chemotherapy would cause serious adverse effects based on her genetic profile. Her doctor selected an alternative — and she started effective treatment from day one.
Accredited by & published in
What you need to know before ordering.
Yes. Consumer MTHFR tests typically check only the C677T and A1298C variants. Whole genome sequencing reads the entire MTHFR gene — plus every other methylation-related gene including MTR, MTRR, COMT, CBS, and BHMT. You get the complete picture, not a partial snapshot.
Whole genome sequencing results are typically delivered in 6–8 weeks once your sample arrives at the lab. You'll receive status updates by email at each step of the process.
Yes. Reports are designed to be physician-ready — formatted for clinical review, not just personal curiosity. You can share reports directly from your Genome Manager account, or download them to bring to an appointment. Dante results have been reviewed and accepted by clinical teams at named institutions including NHS hospitals.
Most MTHFR tests check one or two variants in a single gene. Dante Labs sequences your entire genome at 30X clinical-grade coverage — covering every MTHFR variant plus 200+ additional clinical reports across cardiac, oncology, neurological, pharmacogenomic, and rare disease categories. One test covers everything.
One test. Every variant.
Every answer.
One kit, sent to your home. Your entire genome sequenced at the clinical standard used for diagnostic decisions. 200+ physician-ready reports delivered to your Genome Manager in 6–8 weeks — permanent and updated as science advances. Your raw data — BAM, VCF, and FASTQ — downloadable at any time, forever yours.
Free global shipping · Results in 6–8 weeks
