{
  "url": "https://dantelabs.com/traits/urethral-obstruction",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "urethral-obstruction",
    "id": "HP:0000796",
    "name": "Urethral obstruction",
    "definition": "Obstruction of the flow of urine through the urethra.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormality-of-the-urethra",
        "name": "Urethra issue",
        "url": "https://dantelabs.com/traits/abnormality-of-the-urethra"
      }
    ],
    "narrower": [
      {
        "slug": "urethral-stenosis",
        "name": "Narrowing of the urethra",
        "genes": 41,
        "url": "https://dantelabs.com/traits/urethral-stenosis"
      },
      {
        "slug": "urethral-valve",
        "name": "Urethral valve",
        "genes": 4,
        "url": "https://dantelabs.com/traits/urethral-valve"
      },
      {
        "slug": "urethrovesical-occlusion",
        "name": "Urethrovesical occlusion",
        "genes": 3,
        "url": "https://dantelabs.com/traits/urethrovesical-occlusion"
      }
    ],
    "genes": [
      {
        "slug": "hpse2",
        "symbol": "HPSE2",
        "hgnc": "HGNC:18374",
        "name": "heparanase 2 (inactive)",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/hpse2"
      },
      {
        "slug": "lrig2",
        "symbol": "LRIG2",
        "hgnc": "HGNC:20889",
        "name": "leucine rich repeats and immunoglobulin like domains 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lrig2"
      }
    ]
  }
}