{
  "url": "https://dantelabs.com/traits/ureteral-obstruction",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "ureteral-obstruction",
    "id": "HP:0006000",
    "name": "Ureteral obstruction",
    "definition": "Obstruction of the flow of urine through the ureter.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-ureter-physiology",
        "name": "Abnormal ureter physiology",
        "url": "https://dantelabs.com/traits/abnormal-ureter-physiology"
      }
    ],
    "narrower": [
      {
        "slug": "ureteral-stenosis",
        "name": "Narrowing of the ureter",
        "genes": 10,
        "url": "https://dantelabs.com/traits/ureteral-stenosis"
      }
    ],
    "genes": [
      {
        "slug": "flna",
        "symbol": "FLNA",
        "hgnc": "HGNC:3754",
        "name": "filamin A",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/flna"
      },
      {
        "slug": "grhpr",
        "symbol": "GRHPR",
        "hgnc": "HGNC:4570",
        "name": "glyoxylate and hydroxypyruvate reductase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/grhpr"
      },
      {
        "slug": "map3k7",
        "symbol": "MAP3K7",
        "hgnc": "HGNC:6859",
        "name": "mitogen-activated protein kinase kinase kinase 7",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/map3k7"
      },
      {
        "slug": "lama3",
        "symbol": "LAMA3",
        "hgnc": "HGNC:6483",
        "name": "laminin subunit alpha 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lama3"
      },
      {
        "slug": "lamb3",
        "symbol": "LAMB3",
        "hgnc": "HGNC:6490",
        "name": "laminin subunit beta 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lamb3"
      },
      {
        "slug": "lamc2",
        "symbol": "LAMC2",
        "hgnc": "HGNC:6493",
        "name": "laminin subunit gamma 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lamc2"
      },
      {
        "slug": "atp7a",
        "symbol": "ATP7A",
        "hgnc": "HGNC:869",
        "name": "ATPase copper transporting alpha",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp7a"
      }
    ]
  }
}