{
  "url": "https://dantelabs.com/traits/tarsal-sclerosis",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "tarsal-sclerosis",
    "id": "HP:0031051",
    "name": "Tarsal sclerosis",
    "definition": "An elevation in bone density in one or more tarsal bones of the foot. Sclerosis is normally detected on a radiograph as an area of increased opacity.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-limbs",
        "name": "Abnormality of limbs",
        "url": "https://dantelabs.com/traits/abnormality-of-limbs"
      },
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-tarsal-bone-mineral-density",
        "name": "Abnormal tarsal bone mineral density",
        "url": "https://dantelabs.com/traits/abnormal-tarsal-bone-mineral-density"
      },
      {
        "slug": "sclerosis-of-foot-bone",
        "name": "Increased bone density in foot bone",
        "url": "https://dantelabs.com/traits/sclerosis-of-foot-bone"
      }
    ],
    "narrower": [
      {
        "slug": "tarsal-stippling",
        "name": "Tarsal stippling",
        "genes": 1,
        "url": "https://dantelabs.com/traits/tarsal-stippling"
      }
    ],
    "genes": [
      {
        "slug": "lemd3",
        "symbol": "LEMD3",
        "hgnc": "HGNC:28887",
        "name": "LEM domain containing 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lemd3"
      },
      {
        "slug": "ngly1",
        "symbol": "NGLY1",
        "hgnc": "HGNC:17646",
        "name": "N-glycanase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ngly1"
      }
    ]
  }
}