{
  "url": "https://dantelabs.com/traits/spontaneous-chorioamniotic-separation",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "spontaneous-chorioamniotic-separation",
    "id": "HP:0025712",
    "name": "Spontaneous chorioamniotic separation",
    "definition": "Persistence separation of the chorionic and amnionic membranes after the 16th week of gestation (not as a result of a procedure such as amniocentesis).",
    "synonyms": [
      "Amnion-chorion separation"
    ],
    "systems": [
      {
        "slug": "abnormality-of-prenatal-development-or-birth",
        "name": "Abnormality of prenatal development or birth",
        "url": "https://dantelabs.com/traits/abnormality-of-prenatal-development-or-birth"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-placental-membrane-morphology",
        "name": "Abnormal placental membrane morphology",
        "url": "https://dantelabs.com/traits/abnormal-placental-membrane-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "zmpste24",
        "symbol": "ZMPSTE24",
        "hgnc": "HGNC:12877",
        "name": "zinc metallopeptidase STE24",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zmpste24"
      }
    ]
  }
}