{
  "url": "https://dantelabs.com/traits/segmental-peripheral-demyelination",
  "trait": {
    "bundleId": "2026.10.18-8b139e39",
    "release": "2026-09-01",
    "slug": "segmental-peripheral-demyelination",
    "id": "HP:0007107",
    "name": "Segmental peripheral demyelination",
    "definition": "A loss of myelin from the internode regions along myelinated nerve fibers from segments of the peripheral nervous system.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "peripheral-demyelination",
        "name": "Peripheral demyelination",
        "url": "https://dantelabs.com/traits/peripheral-demyelination"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "gdap1",
        "symbol": "GDAP1",
        "hgnc": "HGNC:15968",
        "name": "ganglioside induced differentiation associated protein 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gdap1"
      },
      {
        "slug": "dnm2",
        "symbol": "DNM2",
        "hgnc": "HGNC:2974",
        "name": "dynamin 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dnm2"
      },
      {
        "slug": "gbf1",
        "symbol": "GBF1",
        "hgnc": "HGNC:4181",
        "name": "golgi brefeldin A resistant guanine nucleotide exchange factor 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gbf1"
      },
      {
        "slug": "sh3tc2",
        "symbol": "SH3TC2",
        "hgnc": "HGNC:29427",
        "name": "SH3 domain and tetratricopeptide repeats 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sh3tc2"
      }
    ]
  }
}