{
  "url": "https://dantelabs.com/traits/renotubular-dysgenesis",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "renotubular-dysgenesis",
    "id": "HP:0008660",
    "name": "Renotubular dysgenesis",
    "definition": "A developmental defect characterized by absence or poor development of proximal renal tubules.",
    "synonyms": [
      "Renal tubular dysgenesis"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-renal-tubule-morphology",
        "name": "Abnormal renal tubule morphology",
        "url": "https://dantelabs.com/traits/abnormal-renal-tubule-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "ace",
        "symbol": "ACE",
        "hgnc": "HGNC:2707",
        "name": "angiotensin I converting enzyme",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ace"
      },
      {
        "slug": "agt",
        "symbol": "AGT",
        "hgnc": "HGNC:333",
        "name": "angiotensinogen",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/agt"
      },
      {
        "slug": "agtr1",
        "symbol": "AGTR1",
        "hgnc": "HGNC:336",
        "name": "angiotensin II receptor type 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/agtr1"
      },
      {
        "slug": "ren",
        "symbol": "REN",
        "hgnc": "HGNC:9958",
        "name": "renin",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ren"
      }
    ]
  }
}