{
  "url": "https://dantelabs.com/traits/recurrent-thrombophlebitis",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "recurrent-thrombophlebitis",
    "id": "HP:0004419",
    "name": "Recurrent thrombophlebitis",
    "definition": "Repeated episodes of inflammation of a vein associated with venous thrombosis (blood clot formation within the vein).",
    "synonyms": [
      "Recurrent phlebitis",
      "Recurrent thrombosis"
    ],
    "systems": [
      {
        "slug": "abnormality-of-blood-and-blood-forming-tissues",
        "name": "Abnormality of blood and blood-forming tissues",
        "url": "https://dantelabs.com/traits/abnormality-of-blood-and-blood-forming-tissues"
      }
    ],
    "broader": [
      {
        "slug": "thrombophlebitis",
        "name": "Thrombophlebitis",
        "url": "https://dantelabs.com/traits/thrombophlebitis"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "aebp1",
        "symbol": "AEBP1",
        "hgnc": "HGNC:303",
        "name": "AE binding protein 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aebp1"
      },
      {
        "slug": "serpinc1",
        "symbol": "SERPINC1",
        "hgnc": "HGNC:775",
        "name": "serpin family C member 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/serpinc1"
      },
      {
        "slug": "tgfb2",
        "symbol": "TGFB2",
        "hgnc": "HGNC:11768",
        "name": "transforming growth factor beta 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tgfb2"
      },
      {
        "slug": "f13a1",
        "symbol": "F13A1",
        "hgnc": "HGNC:3531",
        "name": "coagulation factor XIII A chain",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/f13a1"
      },
      {
        "slug": "f2",
        "symbol": "F2",
        "hgnc": "HGNC:3535",
        "name": "coagulation factor II, thrombin",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/f2"
      },
      {
        "slug": "habp2",
        "symbol": "HABP2",
        "hgnc": "HGNC:4798",
        "name": "hyaluronan binding protein 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/habp2"
      },
      {
        "slug": "mthfr",
        "symbol": "MTHFR",
        "hgnc": "HGNC:7436",
        "name": "methylenetetrahydrofolate reductase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mthfr"
      }
    ]
  }
}