{
  "url": "https://dantelabs.com/traits/poliosis",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "poliosis",
    "id": "HP:0002290",
    "name": "Patch of white hair",
    "label": "Poliosis",
    "definition": "Circumscribed depigmentation of the hair of the head or the eyelashes.",
    "synonyms": [
      "White patch"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "patchy-hypopigmentation-of-hair",
        "name": "Patchy hypopigmentation of hair",
        "url": "https://dantelabs.com/traits/patchy-hypopigmentation-of-hair"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "fas",
        "symbol": "FAS",
        "hgnc": "HGNC:11920",
        "name": "Fas cell surface death receptor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fas"
      },
      {
        "slug": "hla-drb1",
        "symbol": "HLA-DRB1",
        "hgnc": "HGNC:4948",
        "name": "major histocompatibility complex, class II, DR beta 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hla-drb1"
      },
      {
        "slug": "ptpn22",
        "symbol": "PTPN22",
        "hgnc": "HGNC:9652",
        "name": "protein tyrosine phosphatase non-receptor type 22",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ptpn22"
      },
      {
        "slug": "tmco1",
        "symbol": "TMCO1",
        "hgnc": "HGNC:18188",
        "name": "transmembrane and coiled-coil domains 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tmco1"
      }
    ]
  }
}