{
  "url": "https://dantelabs.com/traits/periodic-fever",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "periodic-fever",
    "id": "HP:0032323",
    "name": "Periodic fever",
    "definition": "Episodic fever that recurs at regular intervals.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      }
    ],
    "broader": [
      {
        "slug": "recurrent-fever",
        "name": "Episodic fever",
        "url": "https://dantelabs.com/traits/recurrent-fever"
      }
    ],
    "narrower": [
      {
        "slug": "quotidian-fever",
        "name": "Quotidian fever",
        "genes": 1,
        "url": "https://dantelabs.com/traits/quotidian-fever"
      }
    ],
    "genes": [
      {
        "slug": "lacc1",
        "symbol": "LACC1",
        "hgnc": "HGNC:26789",
        "name": "laccase domain multifunctional purine nucleosidase 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lacc1"
      },
      {
        "slug": "rc3h1",
        "symbol": "RC3H1",
        "hgnc": "HGNC:29434",
        "name": "ring finger and CCCH-type domains 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rc3h1"
      },
      {
        "slug": "rnu2-2",
        "symbol": "RNU2-2",
        "hgnc": "HGNC:10152",
        "name": "RNA, U2 small nuclear 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu2-2"
      },
      {
        "slug": "elane",
        "symbol": "ELANE",
        "hgnc": "HGNC:3309",
        "name": "elastase, neutrophil expressed",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/elane"
      },
      {
        "slug": "nlrp3",
        "symbol": "NLRP3",
        "hgnc": "HGNC:16400",
        "name": "NLR family pyrin domain containing 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nlrp3"
      },
      {
        "slug": "trnt1",
        "symbol": "TRNT1",
        "hgnc": "HGNC:17341",
        "name": "tRNA nucleotidyl transferase 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/trnt1"
      }
    ]
  }
}