{
  "url": "https://dantelabs.com/traits/periapical-bone-loss",
  "trait": {
    "bundleId": "2026.10.18-e609d43e",
    "release": "2026-09-01",
    "slug": "periapical-bone-loss",
    "id": "HP:0000700",
    "name": "Bone loss around tooth root",
    "label": "Periapical bone loss",
    "definition": "Radiolucency (reflecting a reduction in the bony substance) around the apex (the tip of the dental root).",
    "synonyms": [
      "Dark spot around tooth root on x-ray",
      "Periapical lesion"
    ],
    "systems": [
      {
        "slug": "abnormality-of-head-or-neck",
        "name": "Abnormality of head or neck",
        "url": "https://dantelabs.com/traits/abnormality-of-head-or-neck"
      }
    ],
    "broader": [
      {
        "slug": "abnormality-of-the-dentition",
        "name": "Abnormal dentition",
        "url": "https://dantelabs.com/traits/abnormality-of-the-dentition"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "dspp",
        "symbol": "DSPP",
        "hgnc": "HGNC:3054",
        "name": "dentin sialophosphoprotein",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dspp"
      },
      {
        "slug": "smoc2",
        "symbol": "SMOC2",
        "hgnc": "HGNC:20323",
        "name": "SPARC related modular calcium binding 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smoc2"
      }
    ]
  }
}