{
  "url": "https://dantelabs.com/traits/perianal-abscess",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "perianal-abscess",
    "id": "HP:0009789",
    "name": "Perianal abscess",
    "definition": "The presence of an abscess located around the anus.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-digestive-system",
        "name": "Abnormality of the digestive system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-digestive-system"
      },
      {
        "slug": "abnormality-of-the-immune-system",
        "name": "Abnormality of the immune system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-immune-system"
      },
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-anus-morphology",
        "name": "Abnormal anus morphology",
        "url": "https://dantelabs.com/traits/abnormal-anus-morphology"
      },
      {
        "slug": "cutaneous-abscess",
        "name": "Skin abscess",
        "url": "https://dantelabs.com/traits/cutaneous-abscess"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "il10ra",
        "symbol": "IL10RA",
        "hgnc": "HGNC:5964",
        "name": "interleukin 10 receptor subunit alpha",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/il10ra"
      },
      {
        "slug": "sec61a1",
        "symbol": "SEC61A1",
        "hgnc": "HGNC:18276",
        "name": "SEC61 translocon subunit alpha 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sec61a1"
      },
      {
        "slug": "elf4",
        "symbol": "ELF4",
        "hgnc": "HGNC:3319",
        "name": "E74 like ETS transcription factor 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/elf4"
      },
      {
        "slug": "ikzf3",
        "symbol": "IKZF3",
        "hgnc": "HGNC:13178",
        "name": "IKAROS family zinc finger 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ikzf3"
      },
      {
        "slug": "il10rb",
        "symbol": "IL10RB",
        "hgnc": "HGNC:5965",
        "name": "interleukin 10 receptor subunit beta",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/il10rb"
      },
      {
        "slug": "max",
        "symbol": "MAX",
        "hgnc": "HGNC:6913",
        "name": "MYC associated transcriptional regulator X",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/max"
      },
      {
        "slug": "ripk1",
        "symbol": "RIPK1",
        "hgnc": "HGNC:10019",
        "name": "receptor interacting serine/threonine kinase 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ripk1"
      },
      {
        "slug": "tgfb1",
        "symbol": "TGFB1",
        "hgnc": "HGNC:11766",
        "name": "transforming growth factor beta 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tgfb1"
      },
      {
        "slug": "cybc1",
        "symbol": "CYBC1",
        "hgnc": "HGNC:28672",
        "name": "cytochrome b-245 chaperone 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cybc1"
      },
      {
        "slug": "elane",
        "symbol": "ELANE",
        "hgnc": "HGNC:3309",
        "name": "elastase, neutrophil expressed",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/elane"
      },
      {
        "slug": "g6pc3",
        "symbol": "G6PC3",
        "hgnc": "HGNC:24861",
        "name": "glucose-6-phosphatase catalytic subunit 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/g6pc3"
      },
      {
        "slug": "ncf2",
        "symbol": "NCF2",
        "hgnc": "HGNC:7661",
        "name": "neutrophil cytosolic factor 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ncf2"
      },
      {
        "slug": "mnx1",
        "symbol": "MNX1",
        "hgnc": "HGNC:4979",
        "name": "motor neuron and pancreas homeobox 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mnx1"
      }
    ]
  }
}