{
  "url": "https://dantelabs.com/traits/myopic-astigmatism",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "myopic-astigmatism",
    "id": "HP:0500041",
    "name": "Myopic astigmatism",
    "definition": "A condition where one or both of the two principal meridians focus in the front of the retina when the eye is at rest.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-eye",
        "name": "Abnormality of the eye",
        "url": "https://dantelabs.com/traits/abnormality-of-the-eye"
      }
    ],
    "broader": [
      {
        "slug": "astigmatism",
        "name": "Astigmatism",
        "url": "https://dantelabs.com/traits/astigmatism"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "cnga3",
        "symbol": "CNGA3",
        "hgnc": "HGNC:2150",
        "name": "cyclic nucleotide gated channel subunit alpha 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cnga3"
      },
      {
        "slug": "tfe3",
        "symbol": "TFE3",
        "hgnc": "HGNC:11752",
        "name": "transcription factor binding to IGHM enhancer 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tfe3"
      },
      {
        "slug": "vars1",
        "symbol": "VARS1",
        "hgnc": "HGNC:12651",
        "name": "valyl-tRNA synthetase 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/vars1"
      },
      {
        "slug": "arpc4",
        "symbol": "ARPC4",
        "hgnc": "HGNC:707",
        "name": "actin related protein 2/3 complex subunit 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arpc4"
      },
      {
        "slug": "bloc1s3",
        "symbol": "BLOC1S3",
        "hgnc": "HGNC:20914",
        "name": "biogenesis of lysosomal organelles complex 1 subunit 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bloc1s3"
      },
      {
        "slug": "col1a2",
        "symbol": "COL1A2",
        "hgnc": "HGNC:2198",
        "name": "collagen type I alpha 2 chain",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col1a2"
      },
      {
        "slug": "kif11",
        "symbol": "KIF11",
        "hgnc": "HGNC:6388",
        "name": "kinesin family member 11",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kif11"
      }
    ]
  }
}