{
  "url": "https://dantelabs.com/traits/membranous-nephropathy",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "membranous-nephropathy",
    "id": "HP:0012578",
    "name": "Membranous nephropathy",
    "definition": "A type of glomerulonephropathy characterized by thickening of the basement membrane and deposition of immune complexes in the subepithelial space.",
    "synonyms": [
      "Membranous glomerulonephritis"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      },
      {
        "slug": "abnormality-of-the-immune-system",
        "name": "Abnormality of the immune system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-immune-system"
      }
    ],
    "broader": [
      {
        "slug": "glomerulonephritis",
        "name": "Glomerulonephritis",
        "url": "https://dantelabs.com/traits/glomerulonephritis"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "jak1",
        "symbol": "JAK1",
        "hgnc": "HGNC:6190",
        "name": "Janus kinase 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/jak1"
      },
      {
        "slug": "prkcd",
        "symbol": "PRKCD",
        "hgnc": "HGNC:9399",
        "name": "protein kinase C delta",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prkcd"
      },
      {
        "slug": "foxp3",
        "symbol": "FOXP3",
        "hgnc": "HGNC:6106",
        "name": "forkhead box P3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/foxp3"
      },
      {
        "slug": "slc7a7",
        "symbol": "SLC7A7",
        "hgnc": "HGNC:11065",
        "name": "solute carrier family 7 member 7",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc7a7"
      }
    ]
  }
}