{
  "url": "https://dantelabs.com/traits/macular-drusen",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "macular-drusen",
    "id": "HP:0030499",
    "name": "Macular drusen",
    "definition": "Drusen localted in the macula.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-eye",
        "name": "Abnormality of the eye",
        "url": "https://dantelabs.com/traits/abnormality-of-the-eye"
      }
    ],
    "broader": [
      {
        "slug": "drusen",
        "name": "Drusen",
        "url": "https://dantelabs.com/traits/drusen"
      },
      {
        "slug": "yellow-white-macular-lesion",
        "name": "Yellow/white macular lesion",
        "url": "https://dantelabs.com/traits/yellow-white-macular-lesion"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "apoe",
        "symbol": "APOE",
        "hgnc": "HGNC:613",
        "name": "apolipoprotein E",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/apoe"
      },
      {
        "slug": "cfh",
        "symbol": "CFH",
        "hgnc": "HGNC:4883",
        "name": "complement factor H",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfh"
      },
      {
        "slug": "cfhr1",
        "symbol": "CFHR1",
        "hgnc": "HGNC:4888",
        "name": "complement factor H related 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfhr1"
      },
      {
        "slug": "cfhr3",
        "symbol": "CFHR3",
        "hgnc": "HGNC:16980",
        "name": "complement factor H related 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfhr3"
      },
      {
        "slug": "cfi",
        "symbol": "CFI",
        "hgnc": "HGNC:5394",
        "name": "complement factor I",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfi"
      },
      {
        "slug": "efemp1",
        "symbol": "EFEMP1",
        "hgnc": "HGNC:3218",
        "name": "EGF-like fibulin extracellular matrix protein 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/efemp1"
      },
      {
        "slug": "hmcn1",
        "symbol": "HMCN1",
        "hgnc": "HGNC:19194",
        "name": "hemicentin 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hmcn1"
      },
      {
        "slug": "unc119",
        "symbol": "UNC119",
        "hgnc": "HGNC:12565",
        "name": "unc-119 lipid binding chaperone",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/unc119"
      }
    ]
  }
}