{
  "url": "https://dantelabs.com/traits/increased-circulating-free-t3",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "increased-circulating-free-t3",
    "id": "HP:0011788",
    "name": "Increased circulating free T3",
    "definition": "An elevated concentration of free 3,3',5-triiodo-L-thyronine in the blood circulation.",
    "synonyms": [
      "Increased circulating free triiodothyronine",
      "Increased serum free T3",
      "Increased serum free triiodothyronine",
      "Increased serum fT3"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-endocrine-system",
        "name": "Abnormality of the endocrine system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-endocrine-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-circulating-free-t3-concentration",
        "name": "Abnormal circulating free T3 concentration",
        "url": "https://dantelabs.com/traits/abnormal-circulating-free-t3-concentration"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "tg",
        "symbol": "TG",
        "hgnc": "HGNC:11764",
        "name": "thyroglobulin",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tg"
      },
      {
        "slug": "thrb",
        "symbol": "THRB",
        "hgnc": "HGNC:11799",
        "name": "thyroid hormone receptor beta",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/thrb"
      },
      {
        "slug": "tru-tca1-1",
        "symbol": "TRU-TCA1-1",
        "hgnc": "HGNC:12348",
        "name": "tRNA-SeC (anticodon TCA) 1-1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tru-tca1-1"
      },
      {
        "slug": "tshr",
        "symbol": "TSHR",
        "hgnc": "HGNC:12373",
        "name": "thyroid stimulating hormone receptor",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tshr"
      },
      {
        "slug": "slc16a2",
        "symbol": "SLC16A2",
        "hgnc": "HGNC:10923",
        "name": "solute carrier family 16 member 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc16a2"
      }
    ]
  }
}