{
  "url": "https://dantelabs.com/traits/increased-circulating-chylomicron-concentration",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "increased-circulating-chylomicron-concentration",
    "id": "HP:0012238",
    "name": "Increased circulating chylomicron concentration",
    "definition": "Increased plasma concentrations of chylomicrons, the large lipid droplet (up to 100 mm in diameter) of reprocessed lipid synthesized in epithelial cells of the small intestine and containing triacylglycerols, cholesterol esters, and several apolipoproteins.",
    "synonyms": [
      "Hyperchylomicronemia",
      "Increased chylomicrons",
      "Increased circulating chylomicron levels"
    ],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-chylomicron-concentration",
        "name": "Abnormal chylomicron concentration",
        "url": "https://dantelabs.com/traits/abnormal-chylomicron-concentration"
      },
      {
        "slug": "hyperlipoproteinemia",
        "name": "Hyperlipoproteinemia",
        "url": "https://dantelabs.com/traits/hyperlipoproteinemia"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "apoc2",
        "symbol": "APOC2",
        "hgnc": "HGNC:609",
        "name": "apolipoprotein C2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/apoc2"
      },
      {
        "slug": "gpihbp1",
        "symbol": "GPIHBP1",
        "hgnc": "HGNC:24945",
        "name": "glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gpihbp1"
      },
      {
        "slug": "apoa5",
        "symbol": "APOA5",
        "hgnc": "HGNC:17288",
        "name": "apolipoprotein A5",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/apoa5"
      },
      {
        "slug": "lpl",
        "symbol": "LPL",
        "hgnc": "HGNC:6677",
        "name": "lipoprotein lipase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lpl"
      }
    ]
  }
}