{
  "url": "https://dantelabs.com/traits/hyperostosis-frontalis-interna",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "hyperostosis-frontalis-interna",
    "id": "HP:0004438",
    "name": "Thick inner surface of the frontal bone",
    "label": "Hyperostosis frontalis interna",
    "definition": "Bony overgrowth of the internal (endosteal) surface of the frontal bone.",
    "synonyms": [
      "Excessive growth of inner surface of the frontal bone",
      "Hyperostosis of the internal surface of the frontal bone",
      "Overgrowth of the inner surface of the frontal bone"
    ],
    "systems": [
      {
        "slug": "abnormality-of-head-or-neck",
        "name": "Abnormality of head or neck",
        "url": "https://dantelabs.com/traits/abnormality-of-head-or-neck"
      },
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "cranial-hyperostosis",
        "name": "Enlargement of skull bones",
        "url": "https://dantelabs.com/traits/cranial-hyperostosis"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "alms1",
        "symbol": "ALMS1",
        "hgnc": "HGNC:428",
        "name": "ALMS1 centrosome and basal body associated protein",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/alms1"
      },
      {
        "slug": "gnas",
        "symbol": "GNAS",
        "hgnc": "HGNC:4392",
        "name": "GNAS complex locus",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gnas"
      }
    ]
  }
}