{
  "url": "https://dantelabs.com/traits/frontal-release-signs",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "frontal-release-signs",
    "id": "HP:0000743",
    "name": "Frontal release signs",
    "definition": "Primitive reflexes traditionally held to be a sign of disorders that affect the frontal lobes.",
    "synonyms": [
      "Frontal release reflexes"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormality-of-movement",
        "name": "Abnormality of movement",
        "url": "https://dantelabs.com/traits/abnormality-of-movement"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "wdr45",
        "symbol": "WDR45",
        "hgnc": "HGNC:28912",
        "name": "WD repeat domain 45",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/wdr45"
      },
      {
        "slug": "chmp2b",
        "symbol": "CHMP2B",
        "hgnc": "HGNC:24537",
        "name": "charged multivesicular body protein 2B",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chmp2b"
      },
      {
        "slug": "mapt",
        "symbol": "MAPT",
        "hgnc": "HGNC:6893",
        "name": "microtubule associated protein tau",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/mapt"
      },
      {
        "slug": "tbp",
        "symbol": "TBP",
        "hgnc": "HGNC:11588",
        "name": "TATA-box binding protein",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tbp"
      }
    ]
  }
}