{
  "url": "https://dantelabs.com/traits/flattened-epiphysis",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "flattened-epiphysis",
    "id": "HP:0003071",
    "name": "Flat end part of bone",
    "label": "Flattened epiphysis",
    "definition": "Abnormal flatness (decreased height) of epiphyses.",
    "synonyms": [
      "Flat epiphyses"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-epiphysis-morphology",
        "name": "Abnormal shape of end part of bone",
        "url": "https://dantelabs.com/traits/abnormal-epiphysis-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "flattened-femoral-epiphysis",
        "name": "Flattended end part of thigh bone",
        "genes": 2,
        "url": "https://dantelabs.com/traits/flattened-femoral-epiphysis"
      },
      {
        "slug": "flattened-knee-epiphyses",
        "name": "Flattened end part of knee bone",
        "genes": 1,
        "url": "https://dantelabs.com/traits/flattened-knee-epiphyses"
      },
      {
        "slug": "flattened-humeral-epiphyses",
        "name": "Flattened end part of long bone in upper arm",
        "genes": 1,
        "url": "https://dantelabs.com/traits/flattened-humeral-epiphyses"
      },
      {
        "slug": "flattened-radial-epiphyses",
        "name": "Flattened radial epiphyses",
        "genes": 1,
        "url": "https://dantelabs.com/traits/flattened-radial-epiphyses"
      },
      {
        "slug": "flattened-squared-off-epiphyses-of-tubular-bones",
        "name": "Flattened, squared-off end part of tubular bones",
        "genes": 1,
        "url": "https://dantelabs.com/traits/flattened-squared-off-epiphyses-of-tubular-bones"
      }
    ],
    "genes": [
      {
        "slug": "aifm1",
        "symbol": "AIFM1",
        "hgnc": "HGNC:8768",
        "name": "apoptosis inducing factor mitochondria associated 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aifm1"
      },
      {
        "slug": "ift140",
        "symbol": "IFT140",
        "hgnc": "HGNC:29077",
        "name": "intraflagellar transport 140",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ift140"
      },
      {
        "slug": "kif7",
        "symbol": "KIF7",
        "hgnc": "HGNC:30497",
        "name": "kinesin family member 7",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kif7"
      },
      {
        "slug": "pth1r",
        "symbol": "PTH1R",
        "hgnc": "HGNC:9608",
        "name": "parathyroid hormone 1 receptor",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pth1r"
      },
      {
        "slug": "rab33b",
        "symbol": "RAB33B",
        "hgnc": "HGNC:16075",
        "name": "RAB33B, member RAS oncogene family",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rab33b"
      },
      {
        "slug": "col2a1",
        "symbol": "COL2A1",
        "hgnc": "HGNC:2200",
        "name": "collagen type II alpha 1 chain",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/col2a1"
      },
      {
        "slug": "mmp13",
        "symbol": "MMP13",
        "hgnc": "HGNC:7159",
        "name": "matrix metallopeptidase 13",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/mmp13"
      },
      {
        "slug": "slc26a2",
        "symbol": "SLC26A2",
        "hgnc": "HGNC:10994",
        "name": "solute carrier family 26 member 2",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/slc26a2"
      },
      {
        "slug": "slc39a13",
        "symbol": "SLC39A13",
        "hgnc": "HGNC:20859",
        "name": "solute carrier family 39 member 13",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/slc39a13"
      },
      {
        "slug": "cant1",
        "symbol": "CANT1",
        "hgnc": "HGNC:19721",
        "name": "calcium activated nucleotidase 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cant1"
      },
      {
        "slug": "ccn6",
        "symbol": "CCN6",
        "hgnc": "HGNC:12771",
        "name": "cellular communication network factor 6",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ccn6"
      },
      {
        "slug": "chst3",
        "symbol": "CHST3",
        "hgnc": "HGNC:1971",
        "name": "carbohydrate sulfotransferase 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chst3"
      },
      {
        "slug": "col9a2",
        "symbol": "COL9A2",
        "hgnc": "HGNC:2218",
        "name": "collagen type IX alpha 2 chain",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col9a2"
      },
      {
        "slug": "eif2ak3",
        "symbol": "EIF2AK3",
        "hgnc": "HGNC:3255",
        "name": "eukaryotic translation initiation factor 2 alpha kinase 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/eif2ak3"
      },
      {
        "slug": "ift122",
        "symbol": "IFT122",
        "hgnc": "HGNC:13556",
        "name": "intraflagellar transport 122",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ift122"
      },
      {
        "slug": "kif22",
        "symbol": "KIF22",
        "hgnc": "HGNC:6391",
        "name": "kinesin family member 22",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kif22"
      },
      {
        "slug": "slc10a7",
        "symbol": "SLC10A7",
        "hgnc": "HGNC:23088",
        "name": "solute carrier family 10 member 7",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc10a7"
      }
    ]
  }
}