{
  "url": "https://dantelabs.com/traits/facial-asymmetry",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "facial-asymmetry",
    "id": "HP:0000324",
    "name": "Facial asymmetry",
    "definition": "An abnormal difference between the left and right sides of the face.",
    "synonyms": [
      "Asymmetry of face",
      "Crooked face",
      "Unbalanced face",
      "Unequal sides of face",
      "Uneven face",
      "Uneven sides of face",
      "Unsymmetrical face",
      "Asymmetric facies",
      "Asymmetry of right and left side of face"
    ],
    "systems": [
      {
        "slug": "abnormality-of-head-or-neck",
        "name": "Abnormality of head or neck",
        "url": "https://dantelabs.com/traits/abnormality-of-head-or-neck"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-facial-shape",
        "name": "Abnormal facial shape",
        "url": "https://dantelabs.com/traits/abnormal-facial-shape"
      }
    ],
    "narrower": [
      {
        "slug": "craniofacial-asymmetry",
        "name": "Abnormality of craniofacial shape",
        "genes": 6,
        "url": "https://dantelabs.com/traits/craniofacial-asymmetry"
      },
      {
        "slug": "hemifacial-hypoplasia",
        "name": "Decreased size of half of the face",
        "genes": 5,
        "url": "https://dantelabs.com/traits/hemifacial-hypoplasia"
      },
      {
        "slug": "asymmetric-crying-face",
        "name": "Asymmetric crying face",
        "genes": 3,
        "url": "https://dantelabs.com/traits/asymmetric-crying-face"
      },
      {
        "slug": "hemifacial-hypertrophy",
        "name": "Enlargement of half of face",
        "genes": 1,
        "url": "https://dantelabs.com/traits/hemifacial-hypertrophy"
      }
    ],
    "genes": [
      {
        "slug": "chst14",
        "symbol": "CHST14",
        "hgnc": "HGNC:24464",
        "name": "carbohydrate sulfotransferase 14",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chst14"
      },
      {
        "slug": "dhrs3",
        "symbol": "DHRS3",
        "hgnc": "HGNC:17693",
        "name": "dehydrogenase/reductase 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dhrs3"
      },
      {
        "slug": "elmo2",
        "symbol": "ELMO2",
        "hgnc": "HGNC:17233",
        "name": "engulfment and cell motility 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/elmo2"
      },
      {
        "slug": "gusb",
        "symbol": "GUSB",
        "hgnc": "HGNC:4696",
        "name": "glucuronidase beta",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gusb"
      },
      {
        "slug": "kcnk3",
        "symbol": "KCNK3",
        "hgnc": "HGNC:6278",
        "name": "potassium two pore domain channel subfamily K member 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnk3"
      },
      {
        "slug": "neurog1",
        "symbol": "NEUROG1",
        "hgnc": "HGNC:7764",
        "name": "neurogenin 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/neurog1"
      },
      {
        "slug": "piga",
        "symbol": "PIGA",
        "hgnc": "HGNC:8957",
        "name": "phosphatidylinositol glycan anchor biosynthesis class A",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/piga"
      },
      {
        "slug": "pik3ca",
        "symbol": "PIK3CA",
        "hgnc": "HGNC:8975",
        "name": "phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha",
        "frequency": "obligate",
        "diseases": 5,
        "url": "https://dantelabs.com/genes/pik3ca"
      },
      {
        "slug": "rhoa",
        "symbol": "RHOA",
        "hgnc": "HGNC:667",
        "name": "ras homolog family member A",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rhoa"
      },
      {
        "slug": "rnu2-2",
        "symbol": "RNU2-2",
        "hgnc": "HGNC:10152",
        "name": "RNA, U2 small nuclear 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu2-2"
      },
      {
        "slug": "sf3b4",
        "symbol": "SF3B4",
        "hgnc": "HGNC:10771",
        "name": "splicing factor 3b subunit 4",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sf3b4"
      },
      {
        "slug": "slc37a4",
        "symbol": "SLC37A4",
        "hgnc": "HGNC:4061",
        "name": "solute carrier family 37 member 4",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc37a4"
      },
      {
        "slug": "sms",
        "symbol": "SMS",
        "hgnc": "HGNC:11123",
        "name": "spermine synthase",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/sms"
      },
      {
        "slug": "sp7",
        "symbol": "SP7",
        "hgnc": "HGNC:17321",
        "name": "Sp7 transcription factor",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sp7"
      },
      {
        "slug": "tgfbr1",
        "symbol": "TGFBR1",
        "hgnc": "HGNC:11772",
        "name": "transforming growth factor beta receptor 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tgfbr1"
      },
      {
        "slug": "tm2d3",
        "symbol": "TM2D3",
        "hgnc": "HGNC:24128",
        "name": "TM2 domain containing 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tm2d3"
      },
      {
        "slug": "fgfr2",
        "symbol": "FGFR2",
        "hgnc": "HGNC:3689",
        "name": "fibroblast growth factor receptor 2",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/fgfr2"
      },
      {
        "slug": "fgfr3",
        "symbol": "FGFR3",
        "hgnc": "HGNC:3690",
        "name": "fibroblast growth factor receptor 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgfr3"
      },
      {
        "slug": "gdf3",
        "symbol": "GDF3",
        "hgnc": "HGNC:4218",
        "name": "growth differentiation factor 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gdf3"
      },
      {
        "slug": "gdf6",
        "symbol": "GDF6",
        "hgnc": "HGNC:4221",
        "name": "growth differentiation factor 6",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/gdf6"
      },
      {
        "slug": "meox1",
        "symbol": "MEOX1",
        "hgnc": "HGNC:7013",
        "name": "mesenchyme homeobox 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/meox1"
      },
      {
        "slug": "porcn",
        "symbol": "PORCN",
        "hgnc": "HGNC:17652",
        "name": "porcupine O-acyltransferase",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/porcn"
      },
      {
        "slug": "twist1",
        "symbol": "TWIST1",
        "hgnc": "HGNC:12428",
        "name": "twist family bHLH transcription factor 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/twist1"
      },
      {
        "slug": "akt2",
        "symbol": "AKT2",
        "hgnc": "HGNC:392",
        "name": "AKT serine/threonine kinase 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/akt2"
      },
      {
        "slug": "asph",
        "symbol": "ASPH",
        "hgnc": "HGNC:757",
        "name": "aspartate beta-hydroxylase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/asph"
      },
      {
        "slug": "chd7",
        "symbol": "CHD7",
        "hgnc": "HGNC:20626",
        "name": "chromodomain helicase DNA binding protein 7",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/chd7"
      },
      {
        "slug": "chrng",
        "symbol": "CHRNG",
        "hgnc": "HGNC:1967",
        "name": "cholinergic receptor nicotinic gamma subunit",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chrng"
      },
      {
        "slug": "ddx59",
        "symbol": "DDX59",
        "hgnc": "HGNC:25360",
        "name": "DEAD-box helicase 59",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ddx59"
      },
      {
        "slug": "ebp",
        "symbol": "EBP",
        "hgnc": "HGNC:3133",
        "name": "EBP cholestenol delta-isomerase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ebp"
      },
      {
        "slug": "edn1",
        "symbol": "EDN1",
        "hgnc": "HGNC:3176",
        "name": "endothelin 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/edn1"
      },
      {
        "slug": "efnb1",
        "symbol": "EFNB1",
        "hgnc": "HGNC:3226",
        "name": "ephrin B1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/efnb1"
      },
      {
        "slug": "fli1",
        "symbol": "FLI1",
        "hgnc": "HGNC:3749",
        "name": "Fli-1 proto-oncogene, ETS transcription factor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fli1"
      },
      {
        "slug": "flna",
        "symbol": "FLNA",
        "hgnc": "HGNC:3754",
        "name": "filamin A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/flna"
      },
      {
        "slug": "fras1",
        "symbol": "FRAS1",
        "hgnc": "HGNC:19185",
        "name": "Fraser extracellular matrix complex subunit 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fras1"
      },
      {
        "slug": "gnai3",
        "symbol": "GNAI3",
        "hgnc": "HGNC:4387",
        "name": "G protein subunit alpha i3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gnai3"
      },
      {
        "slug": "gon4l",
        "symbol": "GON4L",
        "hgnc": "HGNC:25973",
        "name": "gon-4 like",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gon4l"
      },
      {
        "slug": "h19",
        "symbol": "H19",
        "hgnc": "HGNC:4713",
        "name": "H19 imprinted maternally expressed transcript",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/h19"
      },
      {
        "slug": "hdac9",
        "symbol": "HDAC9",
        "hgnc": "HGNC:14065",
        "name": "histone deacetylase 9",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hdac9"
      },
      {
        "slug": "hras",
        "symbol": "HRAS",
        "hgnc": "HGNC:5173",
        "name": "HRas proto-oncogene, GTPase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hras"
      },
      {
        "slug": "igf2",
        "symbol": "IGF2",
        "hgnc": "HGNC:5466",
        "name": "insulin like growth factor 2",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/igf2"
      },
      {
        "slug": "kat6a",
        "symbol": "KAT6A",
        "hgnc": "HGNC:13013",
        "name": "lysine acetyltransferase 6A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kat6a"
      },
      {
        "slug": "kcnq1ot1",
        "symbol": "KCNQ1OT1",
        "hgnc": "HGNC:6295",
        "name": "KCNQ1 opposite strand/antisense transcript 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnq1ot1"
      },
      {
        "slug": "kmt2a",
        "symbol": "KMT2A",
        "hgnc": "HGNC:7132",
        "name": "lysine methyltransferase 2A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kmt2a"
      },
      {
        "slug": "kras",
        "symbol": "KRAS",
        "hgnc": "HGNC:6407",
        "name": "KRas proto-oncogene, GTPase",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/kras"
      },
      {
        "slug": "lrp4",
        "symbol": "LRP4",
        "hgnc": "HGNC:6696",
        "name": "LDL receptor related protein 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lrp4"
      },
      {
        "slug": "myh3",
        "symbol": "MYH3",
        "hgnc": "HGNC:7573",
        "name": "myosin heavy chain 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/myh3"
      },
      {
        "slug": "nbas",
        "symbol": "NBAS",
        "hgnc": "HGNC:15625",
        "name": "NBAS subunit of NRZ tethering complex",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nbas"
      },
      {
        "slug": "nras",
        "symbol": "NRAS",
        "hgnc": "HGNC:7989",
        "name": "NRAS proto-oncogene, GTPase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nras"
      },
      {
        "slug": "ofd1",
        "symbol": "OFD1",
        "hgnc": "HGNC:2567",
        "name": "OFD1 centriole and centriolar satellite protein",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ofd1"
      },
      {
        "slug": "plcb4",
        "symbol": "PLCB4",
        "hgnc": "HGNC:9059",
        "name": "phospholipase C beta 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/plcb4"
      },
      {
        "slug": "polr1b",
        "symbol": "POLR1B",
        "hgnc": "HGNC:20454",
        "name": "RNA polymerase I subunit B",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/polr1b"
      },
      {
        "slug": "ppp2r1a",
        "symbol": "PPP2R1A",
        "hgnc": "HGNC:9302",
        "name": "protein phosphatase 2 scaffold subunit Aalpha",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ppp2r1a"
      },
      {
        "slug": "psmd12",
        "symbol": "PSMD12",
        "hgnc": "HGNC:9557",
        "name": "proteasome 26S subunit, non-ATPase 12",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/psmd12"
      },
      {
        "slug": "satb2",
        "symbol": "SATB2",
        "hgnc": "HGNC:21637",
        "name": "SATB homeobox 2",
        "frequency": "frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/satb2"
      },
      {
        "slug": "scarf2",
        "symbol": "SCARF2",
        "hgnc": "HGNC:19869",
        "name": "scavenger receptor class F member 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scarf2"
      },
      {
        "slug": "sema3e",
        "symbol": "SEMA3E",
        "hgnc": "HGNC:10727",
        "name": "semaphorin 3E",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sema3e"
      },
      {
        "slug": "sf3b2",
        "symbol": "SF3B2",
        "hgnc": "HGNC:10769",
        "name": "splicing factor 3b subunit 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sf3b2"
      },
      {
        "slug": "smo",
        "symbol": "SMO",
        "hgnc": "HGNC:11119",
        "name": "smoothened, frizzled class receptor",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/smo"
      },
      {
        "slug": "stat3",
        "symbol": "STAT3",
        "hgnc": "HGNC:11364",
        "name": "signal transducer and activator of transcription 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/stat3"
      },
      {
        "slug": "trio",
        "symbol": "TRIO",
        "hgnc": "HGNC:12303",
        "name": "trio Rho guanine nucleotide exchange factor",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/trio"
      },
      {
        "slug": "yy1",
        "symbol": "YY1",
        "hgnc": "HGNC:12856",
        "name": "YY1 transcription factor",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/yy1"
      },
      {
        "slug": "zscan10",
        "symbol": "ZSCAN10",
        "hgnc": "HGNC:12997",
        "name": "zinc finger and SCAN domain containing 10",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zscan10"
      },
      {
        "slug": "adat3",
        "symbol": "ADAT3",
        "hgnc": "HGNC:25151",
        "name": "adenosine deaminase tRNA specific 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/adat3"
      },
      {
        "slug": "akt1",
        "symbol": "AKT1",
        "hgnc": "HGNC:391",
        "name": "AKT serine/threonine kinase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/akt1"
      },
      {
        "slug": "anos1",
        "symbol": "ANOS1",
        "hgnc": "HGNC:6211",
        "name": "anosmin 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/anos1"
      },
      {
        "slug": "bcr",
        "symbol": "BCR",
        "hgnc": "HGNC:1014",
        "name": "BCR activator of RhoGEF and GTPase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bcr"
      },
      {
        "slug": "brca1",
        "symbol": "BRCA1",
        "hgnc": "HGNC:1100",
        "name": "BRCA1 DNA repair associated",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/brca1"
      },
      {
        "slug": "brca2",
        "symbol": "BRCA2",
        "hgnc": "HGNC:1101",
        "name": "BRCA2 DNA repair associated",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/brca2"
      },
      {
        "slug": "brip1",
        "symbol": "BRIP1",
        "hgnc": "HGNC:20473",
        "name": "BRCA1 interacting DNA helicase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/brip1"
      },
      {
        "slug": "cdk13",
        "symbol": "CDK13",
        "hgnc": "HGNC:1733",
        "name": "cyclin dependent kinase 13",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdk13"
      },
      {
        "slug": "cep152",
        "symbol": "CEP152",
        "hgnc": "HGNC:29298",
        "name": "centrosomal protein 152",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cep152"
      },
      {
        "slug": "cep85l",
        "symbol": "CEP85L",
        "hgnc": "HGNC:21638",
        "name": "centrosomal protein 85L",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cep85l"
      },
      {
        "slug": "chn1",
        "symbol": "CHN1",
        "hgnc": "HGNC:1943",
        "name": "chimerin 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chn1"
      },
      {
        "slug": "cltcl1",
        "symbol": "CLTCL1",
        "hgnc": "HGNC:2093",
        "name": "clathrin heavy chain like 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cltcl1"
      },
      {
        "slug": "col1a1",
        "symbol": "COL1A1",
        "hgnc": "HGNC:2197",
        "name": "collagen type I alpha 1 chain",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col1a1"
      },
      {
        "slug": "col2a1",
        "symbol": "COL2A1",
        "hgnc": "HGNC:2200",
        "name": "collagen type II alpha 1 chain",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col2a1"
      },
      {
        "slug": "crkl",
        "symbol": "CRKL",
        "hgnc": "HGNC:2363",
        "name": "CRK like proto-oncogene, adaptor protein",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/crkl"
      },
      {
        "slug": "dact1",
        "symbol": "DACT1",
        "hgnc": "HGNC:17748",
        "name": "dishevelled binding antagonist of beta catenin 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dact1"
      },
      {
        "slug": "dhx37",
        "symbol": "DHX37",
        "hgnc": "HGNC:17210",
        "name": "DEAH-box helicase 37",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dhx37"
      },
      {
        "slug": "ebf3",
        "symbol": "EBF3",
        "hgnc": "HGNC:19087",
        "name": "EBF transcription factor 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ebf3"
      },
      {
        "slug": "elovl4",
        "symbol": "ELOVL4",
        "hgnc": "HGNC:14415",
        "name": "ELOVL fatty acid elongase 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/elovl4"
      },
      {
        "slug": "ercc4",
        "symbol": "ERCC4",
        "hgnc": "HGNC:3436",
        "name": "ERCC excision repair 4, endonuclease catalytic subunit",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ercc4"
      },
      {
        "slug": "eya1",
        "symbol": "EYA1",
        "hgnc": "HGNC:3519",
        "name": "EYA transcriptional coactivator and phosphatase 1",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/eya1"
      },
      {
        "slug": "faap100",
        "symbol": "FAAP100",
        "hgnc": "HGNC:26171",
        "name": "FA core complex associated protein 100",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/faap100"
      },
      {
        "slug": "fanca",
        "symbol": "FANCA",
        "hgnc": "HGNC:3582",
        "name": "FA complementation group A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fanca"
      },
      {
        "slug": "fancb",
        "symbol": "FANCB",
        "hgnc": "HGNC:3583",
        "name": "FA complementation group B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fancb"
      },
      {
        "slug": "fancc",
        "symbol": "FANCC",
        "hgnc": "HGNC:3584",
        "name": "FA complementation group C",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fancc"
      },
      {
        "slug": "fancd2",
        "symbol": "FANCD2",
        "hgnc": "HGNC:3585",
        "name": "FA complementation group D2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fancd2"
      },
      {
        "slug": "fance",
        "symbol": "FANCE",
        "hgnc": "HGNC:3586",
        "name": "FA complementation group E",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fance"
      },
      {
        "slug": "fancf",
        "symbol": "FANCF",
        "hgnc": "HGNC:3587",
        "name": "FA complementation group F",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fancf"
      },
      {
        "slug": "fancg",
        "symbol": "FANCG",
        "hgnc": "HGNC:3588",
        "name": "FA complementation group G",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fancg"
      },
      {
        "slug": "fanci",
        "symbol": "FANCI",
        "hgnc": "HGNC:25568",
        "name": "FA complementation group I",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fanci"
      },
      {
        "slug": "fancl",
        "symbol": "FANCL",
        "hgnc": "HGNC:20748",
        "name": "FA complementation group L",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fancl"
      },
      {
        "slug": "fancm",
        "symbol": "FANCM",
        "hgnc": "HGNC:23168",
        "name": "FA complementation group M",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fancm"
      },
      {
        "slug": "fgf9",
        "symbol": "FGF9",
        "hgnc": "HGNC:3687",
        "name": "fibroblast growth factor 9",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgf9"
      },
      {
        "slug": "fn1",
        "symbol": "FN1",
        "hgnc": "HGNC:3778",
        "name": "fibronectin 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fn1"
      },
      {
        "slug": "gdf5",
        "symbol": "GDF5",
        "hgnc": "HGNC:4220",
        "name": "growth differentiation factor 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gdf5"
      },
      {
        "slug": "gli2",
        "symbol": "GLI2",
        "hgnc": "HGNC:4318",
        "name": "GLI family zinc finger 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gli2"
      },
      {
        "slug": "gnas",
        "symbol": "GNAS",
        "hgnc": "HGNC:4392",
        "name": "GNAS complex locus",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/gnas"
      },
      {
        "slug": "gtf3c3",
        "symbol": "GTF3C3",
        "hgnc": "HGNC:4666",
        "name": "general transcription factor IIIC subunit 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gtf3c3"
      },
      {
        "slug": "idh1",
        "symbol": "IDH1",
        "hgnc": "HGNC:5382",
        "name": "isocitrate dehydrogenase (NADP(+)) 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/idh1"
      },
      {
        "slug": "idh2",
        "symbol": "IDH2",
        "hgnc": "HGNC:5383",
        "name": "isocitrate dehydrogenase (NADP(+)) 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/idh2"
      },
      {
        "slug": "kcnj2",
        "symbol": "KCNJ2",
        "hgnc": "HGNC:6263",
        "name": "potassium inwardly rectifying channel subfamily J member 2",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/kcnj2"
      },
      {
        "slug": "kcnj5",
        "symbol": "KCNJ5",
        "hgnc": "HGNC:6266",
        "name": "potassium inwardly rectifying channel subfamily J member 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnj5"
      },
      {
        "slug": "kdm2b",
        "symbol": "KDM2B",
        "hgnc": "HGNC:13610",
        "name": "lysine demethylase 2B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kdm2b"
      },
      {
        "slug": "kdm4b",
        "symbol": "KDM4B",
        "hgnc": "HGNC:29136",
        "name": "lysine demethylase 4B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kdm4b"
      },
      {
        "slug": "kmt2d",
        "symbol": "KMT2D",
        "hgnc": "HGNC:7133",
        "name": "lysine methyltransferase 2D",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kmt2d"
      },
      {
        "slug": "macf1",
        "symbol": "MACF1",
        "hgnc": "HGNC:13664",
        "name": "microtubule actin crosslinking factor 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/macf1"
      },
      {
        "slug": "mad2l2",
        "symbol": "MAD2L2",
        "hgnc": "HGNC:6764",
        "name": "mitotic arrest deficient 2 like 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mad2l2"
      },
      {
        "slug": "mafb",
        "symbol": "MAFB",
        "hgnc": "HGNC:6408",
        "name": "MAF bZIP transcription factor B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mafb"
      },
      {
        "slug": "man2c1",
        "symbol": "MAN2C1",
        "hgnc": "HGNC:6827",
        "name": "mannosidase alpha class 2C member 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/man2c1"
      },
      {
        "slug": "mapk1",
        "symbol": "MAPK1",
        "hgnc": "HGNC:6871",
        "name": "mitogen-activated protein kinase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mapk1"
      },
      {
        "slug": "nf1",
        "symbol": "NF1",
        "hgnc": "HGNC:7765",
        "name": "neurofibromin 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nf1"
      },
      {
        "slug": "nfix",
        "symbol": "NFIX",
        "hgnc": "HGNC:7788",
        "name": "nuclear factor I X",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nfix"
      },
      {
        "slug": "nog",
        "symbol": "NOG",
        "hgnc": "HGNC:7866",
        "name": "noggin",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nog"
      },
      {
        "slug": "palb2",
        "symbol": "PALB2",
        "hgnc": "HGNC:26144",
        "name": "partner and localizer of BRCA2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/palb2"
      },
      {
        "slug": "piezo2",
        "symbol": "PIEZO2",
        "hgnc": "HGNC:26270",
        "name": "piezo type mechanosensitive ion channel component 2",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/piezo2"
      },
      {
        "slug": "pkd2",
        "symbol": "PKD2",
        "hgnc": "HGNC:9009",
        "name": "polycystin 2, transient receptor potential cation channel",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pkd2"
      },
      {
        "slug": "polr1a",
        "symbol": "POLR1A",
        "hgnc": "HGNC:17264",
        "name": "RNA polymerase I subunit A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/polr1a"
      },
      {
        "slug": "pth1r",
        "symbol": "PTH1R",
        "hgnc": "HGNC:9608",
        "name": "parathyroid hormone 1 receptor",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/pth1r"
      },
      {
        "slug": "pura",
        "symbol": "PURA",
        "hgnc": "HGNC:9701",
        "name": "purine rich element binding protein A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pura"
      },
      {
        "slug": "rad51",
        "symbol": "RAD51",
        "hgnc": "HGNC:9817",
        "name": "RAD51 recombinase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rad51"
      },
      {
        "slug": "rad51c",
        "symbol": "RAD51C",
        "hgnc": "HGNC:9820",
        "name": "RAD51 paralog C",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rad51c"
      },
      {
        "slug": "rfwd3",
        "symbol": "RFWD3",
        "hgnc": "HGNC:25539",
        "name": "ring finger and WD repeat domain 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rfwd3"
      },
      {
        "slug": "rfx7",
        "symbol": "RFX7",
        "hgnc": "HGNC:25777",
        "name": "regulatory factor X7",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rfx7"
      },
      {
        "slug": "sall1",
        "symbol": "SALL1",
        "hgnc": "HGNC:10524",
        "name": "spalt like transcription factor 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sall1"
      },
      {
        "slug": "sall4",
        "symbol": "SALL4",
        "hgnc": "HGNC:15924",
        "name": "spalt like transcription factor 4",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/sall4"
      },
      {
        "slug": "set",
        "symbol": "SET",
        "hgnc": "HGNC:10760",
        "name": "SET nuclear proto-oncogene",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/set"
      },
      {
        "slug": "sin3a",
        "symbol": "SIN3A",
        "hgnc": "HGNC:19353",
        "name": "SIN3 transcription regulator family member A",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/sin3a"
      },
      {
        "slug": "six1",
        "symbol": "SIX1",
        "hgnc": "HGNC:10887",
        "name": "SIX homeobox 1",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/six1"
      },
      {
        "slug": "six5",
        "symbol": "SIX5",
        "hgnc": "HGNC:10891",
        "name": "SIX homeobox 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/six5"
      },
      {
        "slug": "slx4",
        "symbol": "SLX4",
        "hgnc": "HGNC:23845",
        "name": "SLX4 structure-specific endonuclease subunit",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slx4"
      },
      {
        "slug": "smc1a",
        "symbol": "SMC1A",
        "hgnc": "HGNC:11111",
        "name": "structural maintenance of chromosomes 1A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smc1a"
      },
      {
        "slug": "smc3",
        "symbol": "SMC3",
        "hgnc": "HGNC:2468",
        "name": "structural maintenance of chromosomes 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smc3"
      },
      {
        "slug": "son",
        "symbol": "SON",
        "hgnc": "HGNC:11183",
        "name": "SON DNA and RNA binding protein",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/son"
      },
      {
        "slug": "trpm3",
        "symbol": "TRPM3",
        "hgnc": "HGNC:17992",
        "name": "transient receptor potential cation channel subfamily M member 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/trpm3"
      },
      {
        "slug": "ube2t",
        "symbol": "UBE2T",
        "hgnc": "HGNC:25009",
        "name": "ubiquitin conjugating enzyme E2 T",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ube2t"
      },
      {
        "slug": "usp9x",
        "symbol": "USP9X",
        "hgnc": "HGNC:12632",
        "name": "ubiquitin specific peptidase 9 X-linked",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/usp9x"
      },
      {
        "slug": "xrcc2",
        "symbol": "XRCC2",
        "hgnc": "HGNC:12829",
        "name": "X-ray repair cross complementing 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/xrcc2"
      },
      {
        "slug": "cdh11",
        "symbol": "CDH11",
        "hgnc": "HGNC:1750",
        "name": "cadherin 11",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdh11"
      },
      {
        "slug": "ctnnd1",
        "symbol": "CTNND1",
        "hgnc": "HGNC:2515",
        "name": "catenin delta 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ctnnd1"
      },
      {
        "slug": "ppp2r5d",
        "symbol": "PPP2R5D",
        "hgnc": "HGNC:9312",
        "name": "protein phosphatase 2 regulatory subunit B'delta",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ppp2r5d"
      },
      {
        "slug": "rnu4-2",
        "symbol": "RNU4-2",
        "hgnc": "HGNC:10193",
        "name": "RNA, U4 small nuclear 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu4-2"
      },
      {
        "slug": "atr",
        "symbol": "ATR",
        "hgnc": "HGNC:882",
        "name": "ATR checkpoint kinase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atr"
      },
      {
        "slug": "bmp4",
        "symbol": "BMP4",
        "hgnc": "HGNC:1071",
        "name": "bone morphogenetic protein 4",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bmp4"
      },
      {
        "slug": "ednra",
        "symbol": "EDNRA",
        "hgnc": "HGNC:3179",
        "name": "endothelin receptor type A",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ednra"
      },
      {
        "slug": "mycn",
        "symbol": "MYCN",
        "hgnc": "HGNC:7559",
        "name": "MYCN proto-oncogene, bHLH transcription factor",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mycn"
      },
      {
        "slug": "myh8",
        "symbol": "MYH8",
        "hgnc": "HGNC:7578",
        "name": "myosin heavy chain 8",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/myh8"
      },
      {
        "slug": "ntrk2",
        "symbol": "NTRK2",
        "hgnc": "HGNC:8032",
        "name": "neurotrophic receptor tyrosine kinase 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ntrk2"
      },
      {
        "slug": "septin9",
        "symbol": "SEPTIN9",
        "hgnc": "HGNC:7323",
        "name": "septin 9",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/septin9"
      },
      {
        "slug": "slc12a6",
        "symbol": "SLC12A6",
        "hgnc": "HGNC:10914",
        "name": "solute carrier family 12 member 6",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc12a6"
      },
      {
        "slug": "sox5",
        "symbol": "SOX5",
        "hgnc": "HGNC:11201",
        "name": "SRY-box transcription factor 5",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sox5"
      },
      {
        "slug": "zic1",
        "symbol": "ZIC1",
        "hgnc": "HGNC:12872",
        "name": "Zic family zinc finger 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zic1"
      }
    ]
  }
}