{
  "url": "https://dantelabs.com/traits/endocardial-fibroelastosis",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "endocardial-fibroelastosis",
    "id": "HP:0001706",
    "name": "Endocardial fibroelastosis",
    "definition": "Diffuse thickening of the ventricular endocardium and by associated myocardial dysfunction",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-cardiovascular-system",
        "name": "Abnormality of the cardiovascular system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-cardiovascular-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-endocardium-morphology",
        "name": "Abnormal endocardium morphology",
        "url": "https://dantelabs.com/traits/abnormal-endocardium-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "actn2",
        "symbol": "ACTN2",
        "hgnc": "HGNC:164",
        "name": "actinin alpha 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/actn2"
      },
      {
        "slug": "mcm10",
        "symbol": "MCM10",
        "hgnc": "HGNC:18043",
        "name": "minichromosome maintenance 10 replication initiation factor",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mcm10"
      },
      {
        "slug": "nexn",
        "symbol": "NEXN",
        "hgnc": "HGNC:29557",
        "name": "nexilin F-actin binding protein",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nexn"
      },
      {
        "slug": "tafazzin",
        "symbol": "TAFAZZIN",
        "hgnc": "HGNC:11577",
        "name": "tafazzin, phospholipid-lysophospholipid transacylase",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tafazzin"
      },
      {
        "slug": "idua",
        "symbol": "IDUA",
        "hgnc": "HGNC:5391",
        "name": "alpha-L-iduronidase",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/idua"
      },
      {
        "slug": "csrp3",
        "symbol": "CSRP3",
        "hgnc": "HGNC:2472",
        "name": "cysteine and glycine rich protein 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/csrp3"
      },
      {
        "slug": "gja5",
        "symbol": "GJA5",
        "hgnc": "HGNC:4279",
        "name": "gap junction protein alpha 5",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gja5"
      },
      {
        "slug": "slc22a5",
        "symbol": "SLC22A5",
        "hgnc": "HGNC:10969",
        "name": "solute carrier family 22 member 5",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc22a5"
      }
    ]
  }
}