{
  "url": "https://dantelabs.com/traits/early-satiety",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "early-satiety",
    "id": "HP:0033842",
    "name": "Feeling full quickly when eating",
    "label": "Early satiety",
    "definition": "The condition of being unable to eat a full meal because of a feeling of fullness (satiety), or or feeling very full after eating only a small amount of food.",
    "synonyms": [
      "Not able to finish a normal-sized meal"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-digestive-system",
        "name": "Abnormality of the digestive system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-digestive-system"
      }
    ],
    "broader": [
      {
        "slug": "abdominal-symptom",
        "name": "Abdominal symptom",
        "url": "https://dantelabs.com/traits/abdominal-symptom"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "polg",
        "symbol": "POLG",
        "hgnc": "HGNC:9179",
        "name": "DNA polymerase gamma, catalytic subunit",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/polg"
      },
      {
        "slug": "tymp",
        "symbol": "TYMP",
        "hgnc": "HGNC:3148",
        "name": "thymidine phosphorylase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tymp"
      },
      {
        "slug": "alg8",
        "symbol": "ALG8",
        "hgnc": "HGNC:23161",
        "name": "ALG8 alpha-1,3-glucosyltransferase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/alg8"
      },
      {
        "slug": "lrp5",
        "symbol": "LRP5",
        "hgnc": "HGNC:6697",
        "name": "LDL receptor related protein 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lrp5"
      },
      {
        "slug": "prkcsh",
        "symbol": "PRKCSH",
        "hgnc": "HGNC:9411",
        "name": "PRKCSH beta subunit of glucosidase II",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prkcsh"
      },
      {
        "slug": "sec63",
        "symbol": "SEC63",
        "hgnc": "HGNC:21082",
        "name": "SEC63 protein translocation regulator",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sec63"
      },
      {
        "slug": "jak2",
        "symbol": "JAK2",
        "hgnc": "HGNC:6192",
        "name": "Janus kinase 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/jak2"
      },
      {
        "slug": "stat3",
        "symbol": "STAT3",
        "hgnc": "HGNC:11364",
        "name": "signal transducer and activator of transcription 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/stat3"
      }
    ]
  }
}