{
  "url": "https://dantelabs.com/traits/cystathioninuria",
  "trait": {
    "bundleId": "2026.10.16-c6eea6bf",
    "release": "2026-09-01",
    "slug": "cystathioninuria",
    "id": "HP:0003153",
    "name": "High urine cystathionine levels",
    "label": "Cystathioninuria",
    "definition": "An elevated urinary concentration of cystathionine.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      },
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "increased-urinary-non-proteinogenic-amino-acid-level",
        "name": "Increased urinary non-proteinogenic amino acid level",
        "url": "https://dantelabs.com/traits/increased-urinary-non-proteinogenic-amino-acid-level"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "cth",
        "symbol": "CTH",
        "hgnc": "HGNC:2501",
        "name": "cystathionine gamma-lyase",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cth"
      },
      {
        "slug": "lmbrd1",
        "symbol": "LMBRD1",
        "hgnc": "HGNC:23038",
        "name": "LMBR1 domain containing 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lmbrd1"
      },
      {
        "slug": "mmachc",
        "symbol": "MMACHC",
        "hgnc": "HGNC:24525",
        "name": "metabolism of cobalamin associated C",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mmachc"
      },
      {
        "slug": "prdx1",
        "symbol": "PRDX1",
        "hgnc": "HGNC:9352",
        "name": "peroxiredoxin 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prdx1"
      }
    ]
  }
}