{
  "url": "https://dantelabs.com/traits/corneal-crystals",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "corneal-crystals",
    "id": "HP:0000531",
    "name": "Corneal crystals",
    "definition": "Refractile, glittering, or needle-shaped particles said to resemble crystals and located within the corneal epithelium and/or stroma, visible on slit-lamp examination, resulting from the focal accumulation of lipid, protein, or other metabolic material.",
    "synonyms": [
      "Corneal deposits"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-eye",
        "name": "Abnormality of the eye",
        "url": "https://dantelabs.com/traits/abnormality-of-the-eye"
      }
    ],
    "broader": [
      {
        "slug": "opacification-of-the-corneal-stroma",
        "name": "Opacification of the corneal stroma",
        "url": "https://dantelabs.com/traits/opacification-of-the-corneal-stroma"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "ctns",
        "symbol": "CTNS",
        "hgnc": "HGNC:2518",
        "name": "cystinosin, lysosomal cystine transporter",
        "frequency": "obligate",
        "diseases": 6,
        "url": "https://dantelabs.com/genes/ctns"
      },
      {
        "slug": "chst6",
        "symbol": "CHST6",
        "hgnc": "HGNC:6938",
        "name": "carbohydrate sulfotransferase 6",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chst6"
      },
      {
        "slug": "tgfbi",
        "symbol": "TGFBI",
        "hgnc": "HGNC:11771",
        "name": "transforming growth factor beta induced",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tgfbi"
      },
      {
        "slug": "cyp4v2",
        "symbol": "CYP4V2",
        "hgnc": "HGNC:23198",
        "name": "cytochrome P450 family 4 subfamily V member 2",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cyp4v2"
      }
    ]
  }
}