{
  "url": "https://dantelabs.com/traits/cellular-hypersensitivity-to-mitomycin-c",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "cellular-hypersensitivity-to-mitomycin-c",
    "id": "HP:0032188",
    "name": "Cellular hypersensitivity to mitomycin C",
    "definition": "An increased cellular sensitivity to the DNA cross-linking agent, mitomycin C (MMC). In the presence of increased sensitivity, MMC causes increased cell death, chromosome breakage, and accumulation in the G2 phase of the cell cycle.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormal-cellular-phenotype",
        "name": "Abnormal cellular phenotype",
        "url": "https://dantelabs.com/traits/abnormal-cellular-phenotype"
      },
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      }
    ],
    "broader": [
      {
        "slug": "abnormality-of-dna-repair",
        "name": "Abnormality of DNA repair",
        "url": "https://dantelabs.com/traits/abnormality-of-dna-repair"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "faap100",
        "symbol": "FAAP100",
        "hgnc": "HGNC:26171",
        "name": "FA core complex associated protein 100",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/faap100"
      }
    ]
  }
}