{
  "url": "https://dantelabs.com/traits/biliary-tract-neoplasm",
  "trait": {
    "bundleId": "2026.10.16-c6eea6bf",
    "release": "2026-09-01",
    "slug": "biliary-tract-neoplasm",
    "id": "HP:0100574",
    "name": "Biliary tract neoplasm",
    "definition": "A tumor (abnormal growth of tissue) of the biliary system.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-digestive-system",
        "name": "Abnormality of the digestive system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-digestive-system"
      },
      {
        "slug": "neoplasm",
        "name": "Abnormal tissue mass",
        "url": "https://dantelabs.com/traits/neoplasm"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-biliary-tract-morphology",
        "name": "Abnormal biliary tract morphology",
        "url": "https://dantelabs.com/traits/abnormal-biliary-tract-morphology"
      },
      {
        "slug": "neoplasm-of-the-gastrointestinal-tract",
        "name": "Gastrointestinal tract tumor",
        "url": "https://dantelabs.com/traits/neoplasm-of-the-gastrointestinal-tract"
      }
    ],
    "narrower": [
      {
        "slug": "cholangiocarcinoma",
        "name": "Bile duct cancer",
        "genes": 9,
        "url": "https://dantelabs.com/traits/cholangiocarcinoma"
      },
      {
        "slug": "neoplasm-of-the-gallbladder",
        "name": "Neoplasm of the gallbladder",
        "genes": 7,
        "url": "https://dantelabs.com/traits/neoplasm-of-the-gallbladder"
      }
    ],
    "genes": [
      {
        "slug": "brca1",
        "symbol": "BRCA1",
        "hgnc": "HGNC:1100",
        "name": "BRCA1 DNA repair associated",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/brca1"
      },
      {
        "slug": "brca2",
        "symbol": "BRCA2",
        "hgnc": "HGNC:1101",
        "name": "BRCA2 DNA repair associated",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/brca2"
      },
      {
        "slug": "ptpn3",
        "symbol": "PTPN3",
        "hgnc": "HGNC:9655",
        "name": "protein tyrosine phosphatase non-receptor type 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ptpn3"
      },
      {
        "slug": "ros1",
        "symbol": "ROS1",
        "hgnc": "HGNC:10261",
        "name": "ROS proto-oncogene 1, receptor tyrosine kinase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ros1"
      },
      {
        "slug": "stk11",
        "symbol": "STK11",
        "hgnc": "HGNC:11389",
        "name": "serine/threonine kinase 11",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/stk11"
      },
      {
        "slug": "rnf43",
        "symbol": "RNF43",
        "hgnc": "HGNC:18505",
        "name": "ring finger protein 43",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnf43"
      }
    ]
  }
}