{
  "url": "https://dantelabs.com/traits/axillary-freckling",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "axillary-freckling",
    "id": "HP:0000997",
    "name": "Axillary freckling",
    "definition": "The presence in the axillary region (armpit) of an increased number of freckles, small circular spots on the skin that are darker than the surrounding skin because of deposits of melanin.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "freckling",
        "name": "Freckling",
        "url": "https://dantelabs.com/traits/freckling"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "msh6",
        "symbol": "MSH6",
        "hgnc": "HGNC:7329",
        "name": "mutS homolog 6",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/msh6"
      },
      {
        "slug": "nf1",
        "symbol": "NF1",
        "hgnc": "HGNC:7765",
        "name": "neurofibromin 1",
        "frequency": "frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/nf1"
      },
      {
        "slug": "spred1",
        "symbol": "SPRED1",
        "hgnc": "HGNC:20249",
        "name": "sprouty related EVH1 domain containing 1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/spred1"
      },
      {
        "slug": "mlh1",
        "symbol": "MLH1",
        "hgnc": "HGNC:7127",
        "name": "mutL homolog 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mlh1"
      }
    ]
  }
}