{
  "url": "https://dantelabs.com/traits/aspiration-pneumonia",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "aspiration-pneumonia",
    "id": "HP:0011951",
    "name": "Aspiration pneumonia",
    "definition": "Pneumonia due to the aspiration (breathing in) of food, liquid, or gastric contents into the upper respiratory tract.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-immune-system",
        "name": "Abnormality of the immune system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-immune-system"
      },
      {
        "slug": "abnormality-of-the-respiratory-system",
        "name": "Abnormality of the respiratory system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-respiratory-system"
      }
    ],
    "broader": [
      {
        "slug": "pneumonia",
        "name": "Pneumonia",
        "url": "https://dantelabs.com/traits/pneumonia"
      }
    ],
    "narrower": [
      {
        "slug": "recurrent-aspiration-pneumonia",
        "name": "Recurrent aspiration pneumonia",
        "genes": 34,
        "url": "https://dantelabs.com/traits/recurrent-aspiration-pneumonia"
      },
      {
        "slug": "acute-aspiration-pneumonia",
        "name": "Acute aspiration pneumonia",
        "genes": 1,
        "url": "https://dantelabs.com/traits/acute-aspiration-pneumonia"
      }
    ],
    "genes": [
      {
        "slug": "inpp4a",
        "symbol": "INPP4A",
        "hgnc": "HGNC:6074",
        "name": "inositol polyphosphate-4-phosphatase type I A",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/inpp4a"
      },
      {
        "slug": "lrif1",
        "symbol": "LRIF1",
        "hgnc": "HGNC:30299",
        "name": "ligand dependent nuclear receptor interacting factor 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lrif1"
      },
      {
        "slug": "mars2",
        "symbol": "MARS2",
        "hgnc": "HGNC:25133",
        "name": "methionyl-tRNA synthetase 2, mitochondrial",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mars2"
      },
      {
        "slug": "mccc1",
        "symbol": "MCCC1",
        "hgnc": "HGNC:6936",
        "name": "methylcrotonyl-CoA carboxylase subunit 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mccc1"
      },
      {
        "slug": "mdga2",
        "symbol": "MDGA2",
        "hgnc": "HGNC:19835",
        "name": "MAM domain containing glycosylphosphatidylinositol anchor 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mdga2"
      },
      {
        "slug": "pex1",
        "symbol": "PEX1",
        "hgnc": "HGNC:8850",
        "name": "peroxisomal biogenesis factor 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex1"
      },
      {
        "slug": "piga",
        "symbol": "PIGA",
        "hgnc": "HGNC:8957",
        "name": "phosphatidylinositol glycan anchor biosynthesis class A",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/piga"
      },
      {
        "slug": "ptcd3",
        "symbol": "PTCD3",
        "hgnc": "HGNC:24717",
        "name": "pentatricopeptide repeat domain 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ptcd3"
      },
      {
        "slug": "rab32",
        "symbol": "RAB32",
        "hgnc": "HGNC:9772",
        "name": "RAB32, member RAS oncogene family",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rab32"
      },
      {
        "slug": "sdhd",
        "symbol": "SDHD",
        "hgnc": "HGNC:10683",
        "name": "succinate dehydrogenase complex subunit D",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sdhd"
      },
      {
        "slug": "unc13a",
        "symbol": "UNC13A",
        "hgnc": "HGNC:23150",
        "name": "unc-13 homolog A",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/unc13a"
      },
      {
        "slug": "aff4",
        "symbol": "AFF4",
        "hgnc": "HGNC:17869",
        "name": "ALF transcription elongation factor 4",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/aff4"
      },
      {
        "slug": "arid1a",
        "symbol": "ARID1A",
        "hgnc": "HGNC:11110",
        "name": "AT-rich interaction domain 1A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arid1a"
      },
      {
        "slug": "arid1b",
        "symbol": "ARID1B",
        "hgnc": "HGNC:18040",
        "name": "AT-rich interaction domain 1B",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arid1b"
      },
      {
        "slug": "arid2",
        "symbol": "ARID2",
        "hgnc": "HGNC:18037",
        "name": "AT-rich interaction domain 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arid2"
      },
      {
        "slug": "cdon",
        "symbol": "CDON",
        "hgnc": "HGNC:17104",
        "name": "cell adhesion associated, oncogene regulated",
        "frequency": "frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/cdon"
      },
      {
        "slug": "cripto",
        "symbol": "CRIPTO",
        "hgnc": "HGNC:11701",
        "name": "cripto, EGF-CFC family member",
        "frequency": "frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/cripto"
      },
      {
        "slug": "disp1",
        "symbol": "DISP1",
        "hgnc": "HGNC:19711",
        "name": "dispatched RND transporter family member 1",
        "frequency": "frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/disp1"
      },
      {
        "slug": "dll1",
        "symbol": "DLL1",
        "hgnc": "HGNC:2908",
        "name": "delta like canonical Notch ligand 1",
        "frequency": "frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/dll1"
      },
      {
        "slug": "dpf2",
        "symbol": "DPF2",
        "hgnc": "HGNC:9964",
        "name": "double PHD fingers 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dpf2"
      },
      {
        "slug": "fastkd5",
        "symbol": "FASTKD5",
        "hgnc": "HGNC:25790",
        "name": "FASTK mitochondrial RNA regulator 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fastkd5"
      },
      {
        "slug": "fgf8",
        "symbol": "FGF8",
        "hgnc": "HGNC:3686",
        "name": "fibroblast growth factor 8",
        "frequency": "frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/fgf8"
      },
      {
        "slug": "fgfr1",
        "symbol": "FGFR1",
        "hgnc": "HGNC:3688",
        "name": "fibroblast growth factor receptor 1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/fgfr1"
      },
      {
        "slug": "fig4",
        "symbol": "FIG4",
        "hgnc": "HGNC:16873",
        "name": "FIG4 phosphoinositide 5-phosphatase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fig4"
      },
      {
        "slug": "foxh1",
        "symbol": "FOXH1",
        "hgnc": "HGNC:3814",
        "name": "forkhead box H1",
        "frequency": "frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/foxh1"
      },
      {
        "slug": "gas1",
        "symbol": "GAS1",
        "hgnc": "HGNC:4165",
        "name": "growth arrest specific 1",
        "frequency": "frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/gas1"
      },
      {
        "slug": "glb1",
        "symbol": "GLB1",
        "hgnc": "HGNC:4298",
        "name": "galactosidase beta 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/glb1"
      },
      {
        "slug": "gli2",
        "symbol": "GLI2",
        "hgnc": "HGNC:4318",
        "name": "GLI family zinc finger 2",
        "frequency": "frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/gli2"
      },
      {
        "slug": "myo1h",
        "symbol": "MYO1H",
        "hgnc": "HGNC:13879",
        "name": "myosin IH",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/myo1h"
      },
      {
        "slug": "nadk2",
        "symbol": "NADK2",
        "hgnc": "HGNC:26404",
        "name": "NAD kinase 2, mitochondrial",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nadk2"
      },
      {
        "slug": "nfix",
        "symbol": "NFIX",
        "hgnc": "HGNC:7788",
        "name": "nuclear factor I X",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nfix"
      },
      {
        "slug": "nodal",
        "symbol": "NODAL",
        "hgnc": "HGNC:7865",
        "name": "nodal growth differentiation factor",
        "frequency": "frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/nodal"
      },
      {
        "slug": "plch1",
        "symbol": "PLCH1",
        "hgnc": "HGNC:29185",
        "name": "phospholipase C eta 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/plch1"
      },
      {
        "slug": "ptch1",
        "symbol": "PTCH1",
        "hgnc": "HGNC:9585",
        "name": "patched 1",
        "frequency": "frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/ptch1"
      },
      {
        "slug": "samd9",
        "symbol": "SAMD9",
        "hgnc": "HGNC:1348",
        "name": "sterile alpha motif domain containing 9",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/samd9"
      },
      {
        "slug": "shh",
        "symbol": "SHH",
        "hgnc": "HGNC:10848",
        "name": "sonic hedgehog signaling molecule",
        "frequency": "frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/shh"
      },
      {
        "slug": "six3",
        "symbol": "SIX3",
        "hgnc": "HGNC:10889",
        "name": "SIX homeobox 3",
        "frequency": "frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/six3"
      },
      {
        "slug": "smarca4",
        "symbol": "SMARCA4",
        "hgnc": "HGNC:11100",
        "name": "SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smarca4"
      },
      {
        "slug": "smarcb1",
        "symbol": "SMARCB1",
        "hgnc": "HGNC:11103",
        "name": "SWI/SNF related BAF chromatin remodeling complex subunit B1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smarcb1"
      },
      {
        "slug": "smarcc2",
        "symbol": "SMARCC2",
        "hgnc": "HGNC:11105",
        "name": "SWI/SNF related BAF chromatin remodeling complex subunit C2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smarcc2"
      },
      {
        "slug": "smarcd1",
        "symbol": "SMARCD1",
        "hgnc": "HGNC:11106",
        "name": "SWI/SNF related BAF chromatin remodeling complex subunit D1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smarcd1"
      },
      {
        "slug": "smarce1",
        "symbol": "SMARCE1",
        "hgnc": "HGNC:11109",
        "name": "SWI/SNF related BAF chromatin remodeling complex subunit E1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smarce1"
      },
      {
        "slug": "smc1a",
        "symbol": "SMC1A",
        "hgnc": "HGNC:11111",
        "name": "structural maintenance of chromosomes 1A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smc1a"
      },
      {
        "slug": "snap29",
        "symbol": "SNAP29",
        "hgnc": "HGNC:11133",
        "name": "synaptosome associated protein 29",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/snap29"
      },
      {
        "slug": "sox11",
        "symbol": "SOX11",
        "hgnc": "HGNC:11191",
        "name": "SRY-box transcription factor 11",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sox11"
      },
      {
        "slug": "sox4",
        "symbol": "SOX4",
        "hgnc": "HGNC:11200",
        "name": "SRY-box transcription factor 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sox4"
      },
      {
        "slug": "stag2",
        "symbol": "STAG2",
        "hgnc": "HGNC:11355",
        "name": "STAG2 cohesin complex component",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/stag2"
      },
      {
        "slug": "stil",
        "symbol": "STIL",
        "hgnc": "HGNC:10879",
        "name": "STIL centriolar assembly protein",
        "frequency": "frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/stil"
      },
      {
        "slug": "tgif1",
        "symbol": "TGIF1",
        "hgnc": "HGNC:11776",
        "name": "TGFB induced factor homeobox 1",
        "frequency": "frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/tgif1"
      },
      {
        "slug": "zic2",
        "symbol": "ZIC2",
        "hgnc": "HGNC:12873",
        "name": "Zic family zinc finger 2",
        "frequency": "frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/zic2"
      },
      {
        "slug": "acta1",
        "symbol": "ACTA1",
        "hgnc": "HGNC:129",
        "name": "actin alpha 1, skeletal muscle",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/acta1"
      },
      {
        "slug": "atp6v1b2",
        "symbol": "ATP6V1B2",
        "hgnc": "HGNC:854",
        "name": "ATPase H+ transporting V1 subunit B2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp6v1b2"
      },
      {
        "slug": "col4a5",
        "symbol": "COL4A5",
        "hgnc": "HGNC:2207",
        "name": "collagen type IV alpha 5 chain",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col4a5"
      },
      {
        "slug": "col4a6",
        "symbol": "COL4A6",
        "hgnc": "HGNC:2208",
        "name": "collagen type IV alpha 6 chain",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col4a6"
      },
      {
        "slug": "grhl3",
        "symbol": "GRHL3",
        "hgnc": "HGNC:25839",
        "name": "grainyhead like transcription factor 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/grhl3"
      },
      {
        "slug": "hacd1",
        "symbol": "HACD1",
        "hgnc": "HGNC:9639",
        "name": "3-hydroxyacyl-CoA dehydratase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hacd1"
      },
      {
        "slug": "itga7",
        "symbol": "ITGA7",
        "hgnc": "HGNC:6143",
        "name": "integrin subunit alpha 7",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/itga7"
      },
      {
        "slug": "lmnb1",
        "symbol": "LMNB1",
        "hgnc": "HGNC:6637",
        "name": "lamin B1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lmnb1"
      },
      {
        "slug": "map3k20",
        "symbol": "MAP3K20",
        "hgnc": "HGNC:17797",
        "name": "mitogen-activated protein kinase kinase kinase 20",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/map3k20"
      },
      {
        "slug": "myl2",
        "symbol": "MYL2",
        "hgnc": "HGNC:7583",
        "name": "myosin light chain 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/myl2"
      },
      {
        "slug": "ndufa6",
        "symbol": "NDUFA6",
        "hgnc": "HGNC:7690",
        "name": "NADH:ubiquinone oxidoreductase subunit A6",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ndufa6"
      },
      {
        "slug": "pafah1b1",
        "symbol": "PAFAH1B1",
        "hgnc": "HGNC:8574",
        "name": "platelet activating factor acetylhydrolase 1b regulatory subunit 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pafah1b1"
      },
      {
        "slug": "pank2",
        "symbol": "PANK2",
        "hgnc": "HGNC:15894",
        "name": "pantothenate kinase 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pank2"
      },
      {
        "slug": "pla2g6",
        "symbol": "PLA2G6",
        "hgnc": "HGNC:9039",
        "name": "phospholipase A2 group VI",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pla2g6"
      },
      {
        "slug": "pmm2",
        "symbol": "PMM2",
        "hgnc": "HGNC:9115",
        "name": "phosphomannomutase 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pmm2"
      },
      {
        "slug": "pura",
        "symbol": "PURA",
        "hgnc": "HGNC:9701",
        "name": "purine rich element binding protein A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pura"
      },
      {
        "slug": "selenon",
        "symbol": "SELENON",
        "hgnc": "HGNC:15999",
        "name": "selenoprotein N",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/selenon"
      },
      {
        "slug": "taf1",
        "symbol": "TAF1",
        "hgnc": "HGNC:11535",
        "name": "TATA-box binding protein associated factor 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/taf1"
      },
      {
        "slug": "tbc1d24",
        "symbol": "TBC1D24",
        "hgnc": "HGNC:29203",
        "name": "TBC1 domain family member 24",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tbc1d24"
      },
      {
        "slug": "tfg",
        "symbol": "TFG",
        "hgnc": "HGNC:11758",
        "name": "trafficking from ER to golgi regulator",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tfg"
      },
      {
        "slug": "timm8a",
        "symbol": "TIMM8A",
        "hgnc": "HGNC:11817",
        "name": "translocase of inner mitochondrial membrane 8A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/timm8a"
      },
      {
        "slug": "tpm2",
        "symbol": "TPM2",
        "hgnc": "HGNC:12011",
        "name": "tropomyosin 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tpm2"
      },
      {
        "slug": "tpm3",
        "symbol": "TPM3",
        "hgnc": "HGNC:12012",
        "name": "tropomyosin 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tpm3"
      },
      {
        "slug": "ubb",
        "symbol": "UBB",
        "hgnc": "HGNC:12463",
        "name": "ubiquitin B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ubb"
      }
    ]
  }
}