{
  "url": "https://dantelabs.com/traits/annular-cutaneous-lesion",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "annular-cutaneous-lesion",
    "id": "HP:0025528",
    "name": "Annular cutaneous lesion",
    "definition": "A lesion of the skin with a ring-like distribution.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "localized-skin-lesion",
        "name": "Localized skin lesion",
        "url": "https://dantelabs.com/traits/localized-skin-lesion"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "pomp",
        "symbol": "POMP",
        "hgnc": "HGNC:20330",
        "name": "proteasome maturation protein",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pomp"
      },
      {
        "slug": "spink5",
        "symbol": "SPINK5",
        "hgnc": "HGNC:15464",
        "name": "serine peptidase inhibitor Kazal type 5",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/spink5"
      },
      {
        "slug": "ldha",
        "symbol": "LDHA",
        "hgnc": "HGNC:6535",
        "name": "lactate dehydrogenase A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ldha"
      }
    ]
  }
}