{
  "url": "https://dantelabs.com/traits/akinetic-mutism",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "akinetic-mutism",
    "id": "HP:0012672",
    "name": "Akinetic mutism",
    "definition": "The combined absence of spontaneous movement (akinesia) and speech (mutism). There may be eye movements consistent with visual tracking and the person may remember the events occurring at the time of the experience of stupor.",
    "synonyms": [
      "Stuporous mutism"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-diminished-volition",
        "name": "Diminished motivation",
        "url": "https://dantelabs.com/traits/abnormal-diminished-volition"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "dcx",
        "symbol": "DCX",
        "hgnc": "HGNC:2714",
        "name": "doublecortin",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dcx"
      },
      {
        "slug": "prnp",
        "symbol": "PRNP",
        "hgnc": "HGNC:9449",
        "name": "prion protein (Kanno blood group)",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prnp"
      },
      {
        "slug": "htra1",
        "symbol": "HTRA1",
        "hgnc": "HGNC:9476",
        "name": "HtrA serine peptidase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/htra1"
      },
      {
        "slug": "spg21",
        "symbol": "SPG21",
        "hgnc": "HGNC:20373",
        "name": "SPG21 abhydrolase domain containing, maspardin",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/spg21"
      }
    ]
  }
}