{
  "url": "https://dantelabs.com/traits/absent-skin-pigmentation",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "absent-skin-pigmentation",
    "id": "HP:0200098",
    "name": "Absent skin pigmentation",
    "definition": "Lack of skin pigmentation (coloring).",
    "synonyms": [
      "Lack of skin coloration"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "hypopigmentation-of-the-skin",
        "name": "Patchy lightened skin",
        "url": "https://dantelabs.com/traits/hypopigmentation-of-the-skin"
      }
    ],
    "narrower": [
      {
        "slug": "absent-pigmentation-of-chest",
        "name": "Lack of skin coloring on chest",
        "genes": 0,
        "url": "https://dantelabs.com/traits/absent-pigmentation-of-chest"
      }
    ],
    "genes": [
      {
        "slug": "mc1r",
        "symbol": "MC1R",
        "hgnc": "HGNC:6929",
        "name": "melanocortin 1 receptor",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mc1r"
      },
      {
        "slug": "oca2",
        "symbol": "OCA2",
        "hgnc": "HGNC:8101",
        "name": "OCA2 melanosomal transmembrane protein",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/oca2"
      },
      {
        "slug": "tyrp1",
        "symbol": "TYRP1",
        "hgnc": "HGNC:12450",
        "name": "tyrosinase related protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tyrp1"
      },
      {
        "slug": "tyr",
        "symbol": "TYR",
        "hgnc": "HGNC:12442",
        "name": "tyrosinase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tyr"
      }
    ]
  }
}