{
  "url": "https://dantelabs.com/traits/abnormal-macrophage-morphology",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "abnormal-macrophage-morphology",
    "id": "HP:0004311",
    "name": "Abnormal macrophage morphology",
    "definition": "An abnormality of macrophages.",
    "synonyms": [
      "Abnormality of histiocytes",
      "Abnormality of macrophages"
    ],
    "systems": [
      {
        "slug": "abnormality-of-blood-and-blood-forming-tissues",
        "name": "Abnormality of blood and blood-forming tissues",
        "url": "https://dantelabs.com/traits/abnormality-of-blood-and-blood-forming-tissues"
      },
      {
        "slug": "abnormality-of-the-immune-system",
        "name": "Abnormality of the immune system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-immune-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-myeloid-leukocyte-morphology",
        "name": "Abnormal myeloid leukocyte morphology",
        "url": "https://dantelabs.com/traits/abnormal-myeloid-leukocyte-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "hemophagocytosis",
        "name": "Hemophagocytosis",
        "genes": 17,
        "url": "https://dantelabs.com/traits/hemophagocytosis"
      },
      {
        "slug": "granulomatosis",
        "name": "Granulomatosis",
        "genes": 11,
        "url": "https://dantelabs.com/traits/granulomatosis"
      },
      {
        "slug": "histiocytosis",
        "name": "Histiocytosis",
        "genes": 6,
        "url": "https://dantelabs.com/traits/histiocytosis"
      },
      {
        "slug": "bone-marrow-foam-cells",
        "name": "Bone-marrow foam cells",
        "genes": 5,
        "url": "https://dantelabs.com/traits/bone-marrow-foam-cells"
      },
      {
        "slug": "sea-blue-histiocytosis",
        "name": "Sea-blue histiocytosis",
        "genes": 5,
        "url": "https://dantelabs.com/traits/sea-blue-histiocytosis"
      }
    ],
    "genes": [
      {
        "slug": "samd9l",
        "symbol": "SAMD9L",
        "hgnc": "HGNC:1349",
        "name": "sterile alpha motif domain containing 9 like",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/samd9l"
      },
      {
        "slug": "sgcg",
        "symbol": "SGCG",
        "hgnc": "HGNC:10809",
        "name": "sarcoglycan gamma",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sgcg"
      }
    ]
  }
}