{
  "url": "https://dantelabs.com/traits/abnormal-hippocampus-morphology",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "abnormal-hippocampus-morphology",
    "id": "HP:0025100",
    "name": "Abnormal hippocampus morphology",
    "definition": "Any structural anomaly of the hippocampus,",
    "synonyms": [
      "Abnormal morphology of the hippocampus",
      "Abnormality of hippocampus morphology"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-morphology-of-the-limbic-system",
        "name": "Abnormal morphology of the limbic system",
        "url": "https://dantelabs.com/traits/abnormal-morphology-of-the-limbic-system"
      }
    ],
    "narrower": [
      {
        "slug": "hypoplastic-hippocampus",
        "name": "Small hippocampus",
        "genes": 19,
        "url": "https://dantelabs.com/traits/hypoplastic-hippocampus"
      },
      {
        "slug": "dysgenesis-of-the-hippocampus",
        "name": "Dysgenesis of the hippocampus",
        "genes": 16,
        "url": "https://dantelabs.com/traits/dysgenesis-of-the-hippocampus"
      },
      {
        "slug": "hippocampal-atrophy",
        "name": "Hippocampal atrophy",
        "genes": 11,
        "url": "https://dantelabs.com/traits/hippocampal-atrophy"
      },
      {
        "slug": "hippocampal-malrotation",
        "name": "Hippocampal malrotation",
        "genes": 5,
        "url": "https://dantelabs.com/traits/hippocampal-malrotation"
      },
      {
        "slug": "hippocampal-sclerosis",
        "name": "Hippocampal sclerosis",
        "genes": 3,
        "url": "https://dantelabs.com/traits/hippocampal-sclerosis"
      },
      {
        "slug": "absent-hippocampal-commissure",
        "name": "Absent hippocampal commissure",
        "genes": 1,
        "url": "https://dantelabs.com/traits/absent-hippocampal-commissure"
      }
    ],
    "genes": [
      {
        "slug": "cep85l",
        "symbol": "CEP85L",
        "hgnc": "HGNC:21638",
        "name": "centrosomal protein 85L",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cep85l"
      },
      {
        "slug": "macf1",
        "symbol": "MACF1",
        "hgnc": "HGNC:13664",
        "name": "microtubule actin crosslinking factor 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/macf1"
      },
      {
        "slug": "zeb2",
        "symbol": "ZEB2",
        "hgnc": "HGNC:14881",
        "name": "zinc finger E-box binding homeobox 2",
        "frequency": "frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/zeb2"
      },
      {
        "slug": "grin1",
        "symbol": "GRIN1",
        "hgnc": "HGNC:4584",
        "name": "glutamate ionotropic receptor NMDA type subunit 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/grin1"
      },
      {
        "slug": "vps13a",
        "symbol": "VPS13A",
        "hgnc": "HGNC:1908",
        "name": "vacuolar protein sorting 13 homolog A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/vps13a"
      },
      {
        "slug": "nr2f1",
        "symbol": "NR2F1",
        "hgnc": "HGNC:7975",
        "name": "nuclear receptor subfamily 2 group F member 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nr2f1"
      }
    ]
  }
}